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KCNA3

potassium voltage-gated channel, shaker-related subfamily, member 3

Synonyme:
HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3738) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]
  • Mouse(16491) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Rat(29731) potassium voltage-gated channel, shaker-related subfamily, member 3
  • cow(525507) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic cat(101092201) potassium voltage-gated channel, shaker-related subfamily, member 3
  • dog(490110) potassium voltage-gated channel, shaker-related subfamily, member 3
  • chicken(404303) potassium voltage-gated channel, shaker-related subfamily, member 3
  • naked mole-rat(101719045) potassium voltage-gated channel, shaker-related subfamily, member 3
  • domestic guinea pig(100721847) potassium voltage-gated channel, shaker-related subfamily, member 3
  • sheep(101105466) potassium voltage-gated channel, shaker-related subfamily, member 3
  • Domestic Rabbit(100328945) potassium voltage-gated channel, shaker-related subfamily, member 3

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Potassium Channel Kv1.3 Antibody, extracellular domain, Chemicon®, from rabbit,
Speziesreaktivität
human, rat
Anwendung
flow cytometry
western blot
Anti-KV1.3 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry
Anti-phospho-Kv1.3/KCNA3 (pTyr135) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-KCNA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Potassium Channel Kv1.3 Antibody, Chemicon®, from rabbit,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Charybdotoxin, ≥90% (HPLC),
Spezies
mouse, rat, human
Guanidin -hydrochlorid, for molecular biology, ≥99%,
Spezies
human
Guanidin -hydrochlorid, ≥98%,
Spezies
human
Guanidin -hydrochlorid, ≥99% (titration), organic base and chaeotropic agent,
Spezies
human
Guanidin -hydrochlorid, ,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human KCNA3,
Spezies
human