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Merck

FLNA

filamin A, alpha

Synonyme:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
  • Mouse(192176) filamin, alpha
  • Rat(293860) filamin A, alpha
  • domestic guinea pig(100725162) filamin A, alpha
  • Zebrafish(562529) filamin A, alpha (actin binding protein 280)
  • chicken(395261) filamin A, alpha
  • naked mole-rat(101702004) filamin A, alpha
  • Zebrafish(100534866) filamin A, alpha
  • sheep(101120390) filamin A, alpha
  • dog(481084) filamin A, alpha
  • Domestic Rabbit(100328754) filamin A, alpha
  • cow(281165) filamin A, alpha
  • domestic cat(101082637) filamin A, alpha

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Filamin A Antibody, clone PM6/317 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Filamin-A-Antikörper, Klon TI10, ascites fluid, clone TI10, Chemicon®,
Speziesreaktivität
bovine, human
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Filamin antibody,Mouse monoclonal, clone PM6/317, purified from hybridoma cell culture,
Speziesreaktivität
bovine, canine, hamster, human, monkey
Anwendung
immunofluorescence
western blot
Anti-Filamin-A-Antikörper, Klon TI10, aszitesfrei, clone TI10, 1 mg/mL, from mouse,
Speziesreaktivität
bovine, human
Anwendung
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-FLNA antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human FLNA,
Spezies
human