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Merck

CYP26A1

cytochrome P450, family 26, subfamily A, polypeptide 1

Synonyme:
CP26, CYP26, P450RAI, P450RAI1
Spezies:
Human CYP26A1 (1592), Mouse Cyp26a1 (13082), Rat Cyp26a1 (154985), Zebrafish cyp26a1 (30381), cow CYP26A1 (539047), chicken CYP26A1 (408183), dog CYP26A1 (486804)
UniProtKB-ID:
O43174, B3KNI4, Q5VXH9, Q5VXI0
Gen-ID:
  • Human(1592) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(13082) cytochrome P450, family 26, subfamily a, polypeptide 1
  • Rat(154985) cytochrome P450, family 26, subfamily a, polypeptide 1
  • Zebrafish(30381) cytochrome P450, subfamily XXVIA, polypeptide 1
  • cow(539047) cytochrome P450, family 26, subfamily A, polypeptide 1
  • chicken(408183) cytochrome P450, family 26, subfamily A, polypeptide 1
  • dog(486804) cytochrome P450, family 26, subfamily A, polypeptide 1

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB5701622
Anti-CYP26A1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
SAB1300686
Anti-CYP26A1 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
K1003
Ketoconazol, 99.0-101.0% (EP, titration),
Spezies
mouse, human, rat

esiRNA

Produktnummer
Beschreibung
Spezies
EMU033671
MISSION® esiRNA, targeting mouse Cyp26a1,
Spezies
mouse
EHU133401
MISSION® esiRNA, targeting human CYP26A1,
Spezies
human