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CDK1

cyclin-dependent kinase 1

Synonyme:
CDC2, CDC28A, P34CDC2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(12534) cyclin-dependent kinase 1
  • Rat(54237) cyclin-dependent kinase 1
  • dog(488997) cyclin-dependent kinase 1
  • Zebrafish(80973) cyclin-dependent kinase 1
  • chicken(396252) cyclin-dependent kinase 1
  • naked mole-rat(101717463) cyclin-dependent kinase 1
  • domestic guinea pig(100735946) cyclin-dependent kinase 1
  • Goat(100861361) cyclin-dependent kinase 1
  • cow(281061) cyclin-dependent kinase 1
  • sheep(100216432) cyclin-dependent kinase 1

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Phospho-CDK1-T14 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
western blot
Anti-phospho-Cdk1 (Thr14, Tyr15)Antibody, clone CP3.2, clone CP3.2, from mouse,
Speziesreaktivität
human
Anwendung
immunocytochemistry
western blot
Anti-Phospho-CDK1-T161 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse
Anwendung
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-phospho-CDC2 (pThr161) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-CDC2 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
R547, ≥98% (HPLC),
Spezies
human
Flavopiridol -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
Roscovitine, ≥98% (TLC),
Spezies
human, mouse, rat

Proteins

Produktnummer
Beschreibung
Spezies
CDK1/CyclinB1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human
CDK1/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CDK1,
Spezies
human