M2699

Marimastat

≥98% (HPLC), solid, MMP inhibitor

• Synonym(s): BB2516, (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl] propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
• Empirical Formula (Hill Notation): C₁₅H₂₉N₃O₅
• CAS Number: 154039-60-8
• Molecular Weight: 331.41
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817950
• NACRES: NA.77
• MDL number: MFCD00866242
• Assay: ≥98% (HPLC)
• Form: solid

Properties

• Product Name: Marimastat, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• solubility: DMSO: ≥20 mg/mL
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C
• InChI: 1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
• InChI key: OCSMOTCMPXTDND-OUAUKWLOSA-N
• Gene Information: —

Description

Application

Marimastat has been used as an inhibitor of:

• metalloproteinase 2/9 (MMP2/9), to study its effects on exercise-mediated interleukin-6 (IL-6) release in mice
• metalloproteinase, to determine protease activity in Pseudomonas aeruginosa cultures
• metalloproteinase 10 (MMP10), to study its effect on monoclonal antibody H3 binding to MMP10

Biochem/physiol Actions

Marimastat is a broad spectrum matrix metalloprotease (MMP) inhibitor

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable