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H159

Supelco

Heroin

analytical standard, ≥98% (HPLC)

Synonym(s):

Diacetylmorphine

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About This Item

Empirical Formula (Hill Notation):
C21H23NO5
CAS Number:
561-27-3
Molecular Weight:
369.41
EC Number:
209-217-7
MDL number:
MFCD00468072
UNSPSC Code:
41116107
PubChem Substance ID:
329815171
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

Assay

≥98% (HPLC)

form

powder

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

storage condition

desiccated

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

color

white to beige

solubility

H2O: <0.2 mg/mL
DMSO: 5 mg/mL, clear
ethanol: 6 mg/mL
0.1 M HCl: <6.67 mg/mL

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CN1CC[C@]23[C@H]4Oc5c(OC(C)=O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1

InChI key

GVGLGOZIDCSQPN-PVHGPHFFSA-N

Related Categories

General description

Heroin is a highly addictive illicit drug and opioid agonist, widely used in medical applications as an analgesic.[1]

Application

Heroin may be used as a standard to determine the amount of heroin present in clandestine heroin samples using capillary zone electrophoresis (CZE) technique. Heroin may be used as an analytical reference standard for the quantification of the analyte in biological samples[2][3] using different chromatography techniques.
Heroin may be used as a standard to determine the amount of heroin present in clandestine heroin samples using capillary zone electrophoresis (CZE) technique.[4]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300 + H310 + H330

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000341823
0000341823
0000240298
0000182100
0000182100

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Nature communications, 10(1), 4140-4140 (2019-09-14)
Persistent transcriptional and morphological events in the nucleus accumbens (NAc) and other brain reward regions contribute to the long-lasting behavioral adaptations that characterize drug addiction. Opiate exposure reduces the density of dendritic spines on medium spiny neurons of the NAc;
Diacetylmorphine degradation to 6-monoacetylmorphine and morphine in cell culture: implications for in vitro studies
Hutchinson.RM, et al.
European Journal of Pharmacology, 453(1), 27-32 (2002)
Stanley Luchters et al.
BMC public health, 11, 384-384 (2011-05-26)
Previous research has linked alcohol use with an increased number of sexual partners, inconsistent condom use and a raised incidence of sexually transmitted infections (STIs). However, alcohol measures have been poorly standardised, with many ill-suited to eliciting, with adequate precision
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Infectious diseases (London, England), 52(5), 336-346 (2020-02-20)
Background and aims: Sharing of unsterile injection equipment contributes to transmission of hepatitis C virus (HCV), HIV and hepatitis B virus (HBV) among people who inject drugs (PWID) but is largely preventable through needle exchange programmes (NEP). Sweden has been
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