The minimum Sapogenin content for this product is 20%. This information is lot-specific and reported in the Certificate of Analysis. A review of recent lots indicates a typical range of 21 - 26% Sapogenin. Please see the link below to review a lot-specific Certificate:
https://www.sigmaaldrich.com/product/mm/558255#product-documentation
558255
Saponin
A glycoside used to permeabilize cellular membranes. Exhibits hemolytic activity.
Synonym(s):
Saponin
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About This Item
Pricing and availability is not currently available.
Quality Segment
description
Merck USA index - 14, 8365
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤10% ash
color
tan
solubility
water: soluble
shipped in
ambient
storage temp.
15-25°C
SMILES string
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C(=O)O)O[C@@H]3[C@@](C4[C@@](C5[C@]([C@@]6(C[C@H]([C@]7([C@H]([C@@H](C(CC7C6=CC5)(C)C)OC(=O)\C(=C/C)\C)OC(=O)C)CO)O)C)(CC4)C)(CC3)C
InChI
1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(1
InChI key
AXNVHPCVMSNXNP-ZELRDNAQSA-N
General description
A glycoside used to permeabilize cellular membranes. Exhibits hemolytic activity.
Application
- Complete biosynthesis of QS-21 in engineered yeast.: This article reports the successful biosynthesis of QS-21, a potent saponin adjuvant, in engineered yeast. The research highlights the potential for scalable and sustainable production of QS-21, which is crucial for vaccine development and immunotherapy. (Liu et al., 2024).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
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This Item | |||
|---|---|---|---|
| form solid | form powder | form - | form - |
| storage temp. 15-25°C | storage temp. - | storage temp. - | storage temp. - |
| solubility water: soluble | solubility water: 1 g/10 mL, clear to hazy, yellow to brown | solubility - | solubility - |
| impurities ≤10% ash | impurities ≤20% sulphated ash | impurities - | impurities - |
| description Merck USA index - 14, 8365 | description - | description - | description non-ionic |
| Quality Level 100 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 558255-100GM | 07790788051525 |
| 558255-5KG | 04061839404762 |
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what % of this saponin is composed of sapogenin?
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Hi All, please, is this product suitable to detect bone marrow cell cycle in mice? Regards, Ahmad
1 answer-
This product has not been tested for suitability to detect bone marrow cell cycle in mice. This is an application that will need to be determined by the end-user.
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