This product is not sterile. Prepared solutions may be filter sterilized.
D0627
Monofosfato de N6,2′-O-dibutiriladenosina 3′,5′-cíclico sodium salt
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt
≥96% (HPLC), powder
Sinónimos:
Bucladesina sodium salt, Dibutirilo del AMP cíclico sodium salt, Dibutirilo del AMPc sodium salt
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25 MG
US$ 103,00
100 MG
US$ 316,00
250 MG
US$ 511,00
1 G
US$ 1.630,00
5 X 1 G
US$ 6.180,00
Seleccione un Tamaño
Cambiar Vistas
25 MG
US$ 103,00
100 MG
US$ 316,00
250 MG
US$ 511,00
1 G
US$ 1.630,00
5 X 1 G
US$ 6.180,00
About This Item
Fórmula lineal:
C18H23N5O8PNa
Número de CAS:
Peso molecular:
491.37
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Productos recomendados
biological source
synthetic (organic)
Quality Level
assay
≥96% (HPLC)
form
powder
impurities
≤0.5% Cyclic AMP
≤3% monobutyryl derivatives
color
off-white
solubility
H2O: 100 mg/mL
storage temp.
−20°C
SMILES string
[Na+].CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3OC(=O)CCC
InChI
1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24);/q;+1/p-1/t10-,14-,15-,18-;/m1./s1
InChI key
KRBZRVBLIUDQNG-JBVYASIDSA-M
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Categorías relacionadas
Application
El dibutirilo de AMPc es un análogo permeable a la célula del AMPc que activa la proteíncinasa (PKA) dependiente del AMPc o la vía de señalización AMPc/PKA. El dibutirilo de AMPc se utiliza como inductor de la diferenciación morfológica y modulador de la comunicación celular en células como las de Schwann. El dibutirilo de AMPc se utiliza en una variedad de estudios de diferenciación, como la diferenciación neuronal.
Biochem/physiol Actions
Análogo del AMPc permeable a la célula que activa las proteincinasas (PKA) dependientes del AMPc.
Caution
Pierde el grupo 2′-O-butirilo a pH 8,5
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Protocolos
Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.
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is this product sterile?
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Helpful?
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How long is it stable in -20ºC after reconstitution in DMSO or H2O at 200mM? Do you have any recommendations for stability once the product is in solution?
1 answer-
This product is soluble in water at 100 mg/mL. The solubility in DMSO has not been determined. Following reconstitution, aliquot and freeze at -20°C for up to 3 months or refrigerate at 2 - 8°C for up to 3 days. Avoid pH of 8.5 or greater as hydrolysis will occur. Please see the link below to review the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/368/353/d0627pis-ms.pdfHelpful?
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