L3042

Levocabastine hydrochloride

≥99% (HPLC), solid

• Sinónimos: Levophta, Levostin, R50547, [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid
• Fórmula empírica (notación de Hill): C₂₆H₂₉N₂O₂F·HCl
• Número de CAS: 79547-78-7
• Peso molecular: 456.98
• MDL number: MFCD07787408
• UNSPSC Code: 12352200
• PubChem Substance ID: 329817402

Propiedades

• assay: ≥99% (HPLC)
• form: solid
• color: white
• solubility: DMSO: soluble ~10 mg/mL
• originator: Johnson & Johnson
• SMILES string: Cl[H].C[C@@H]1CN(CC[C@]1(C(O)=O)c2ccccc2)[C@@H]3CC[C@@](CC3)(C#N)c4ccc(F)cc4
• InChI: 1S/C26H29FN2O2.ClH/c1-19-17-29(16-15-26(19,24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,14-12-23)20-7-9-22(27)10-8-20;/h2-10,19,23H,11-17H2,1H3,(H,30,31);1H/t19-,23-,25-,26-;/m1./s1
• InChI key: OICFWWJHIMKBCD-VALQNVSPSA-N
• Gene Information: human ... HRH1(3269)

Descripción

Biochem/physiol Actions

Non-peptide histamine H₁ receptor antagonist; neurotensin NTS₂ receptor ligand.

Features and Benefits

This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves