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Merck
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Documentos clave

A1900

Sigma-Aldrich

Albumin, Monomer bovine

Monomer ≥97 %

Sinónimos:

Albumin powder, Bovine albumins

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About This Item

Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
12352202
eCl@ss:
42010201
NACRES:
NA.26
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origen biológico

bovine

Ensayo

≥97% (PAGE)

Formulario

lyophilized powder

composición

Monomer, ≥97%

técnicas

SDS-PAGE: suitable

solubilidad

H2O: soluble 50 mg/mL

Nº de acceso UniProt

temp. de almacenamiento

2-8°C

Información sobre el gen

bovine ... ALB(280717)

Descripción general

The most abundant plasma protein in mammals is albumin. It is produced in the liver and transferred as a non-glycosylated protein into the plasma. This multifunctional protein can bind to ligands. [1]

Aplicación

Albumin, Monomer bovine has been used as a:
  • molecular weight (MW) and polydispersion index (PDI) reference standard for the analysis of hyaluronic acid (HA)-based eye drops[2]
  • standard in multi-angle light scattering coupled with size exclusion chromatography (SEC-MALS) for calibration[3]
  • model protein to generate subvisible particles (SVPs) for flow imaging microscopy studies[4]

The binding properties of albumin can be used for a wide range of clinical, pharmaceutical, and biochemical applications.[1]

Acciones bioquímicas o fisiológicas

Albumin is the most important circulatory protein involved in the control of Ca2+ (and Mg2+) levels in mammals.[1]

Nota de preparación

Isolated from albumin (A4503) as described for mercaptalbumin in Janatova, J., et al., J. Biol. Chem., 243, 3612 (1968).

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Secondary structural change of bovine serum albumin in thermal denaturation up to 130 degrees C and protective effect of sodium dodecyl sulfate on the change.
Moriyama, Y., et al.
The Journal of Physical Chemistry B, 112, 16585-16589 (2008)
Pasquale Aragona et al.
Translational vision science & technology, 8(6), 2-2 (2019-11-07)
To assess the physicochemical properties of hyaluronic acid (HA)-based artificial tears. The average molecular weight (MW) and polydispersion index (PDI) of HA in 18 commercially available artificial tears were determined by light scattering/high-performance liquid chromatography. Osmolality, pH, viscosity, and sodium
Manuel Maestre-Reyna et al.
IUBMB life, 73(2), 418-431 (2020-12-30)
Vibrio cholerae is the causative agent of the diarrheal disease cholera, for which biofilm communities are considered to be environmental reservoirs. In endemic regions, and after algal blooms, which may result from phosphate enrichment following agricultural runoff, the bacterium is
Surendra Dasari et al.
Journal of proteome research, 8(3), 1263-1270 (2009-01-29)
A robust peptide quantification method was developed where overlapping peptide isotopic distributions were fit with predicted peptide isotopic envelope mixture models (IEMMs). Application to two difficult quantitative problems was demonstrated. The first was the quantification of deamidation, where masses of
Joe A Kaczmarski et al.
Nature communications, 11(1), 5945-5945 (2020-11-25)
Several enzymes are known to have evolved from non-catalytic proteins such as solute-binding proteins (SBPs). Although attention has been focused on how a binding site can evolve to become catalytic, an equally important question is: how do the structural dynamics

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