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Merck

90151

Supelco

17β-Hydroxy-17-methylandrosta-1,4-dien-3-one

analytical standard

Sinónimos:

1-Dehydro-17α-methyltestosterone, Dianabol, Methandienone, Methandrostenolone

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About This Item

Fórmula empírica (notación de Hill):
C20H28O2
Número de CAS:
Peso molecular:
300.44
Beilstein/REAXYS Number:
2056255
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥97.0% (HPLC)

optical activity

[α]1.15/D -0.5±0.5° in chloroform

shelf life

limited shelf life, expiry date on the label

drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

functional group

ketone

storage temp.

2-8°C

SMILES string

C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C20H28O2/c1-18-9-6-14(21)12-13(18)4-5-15-16(18)7-10-19(2)17(15)8-11-20(19,3)22/h6,9,12,15-17,22H,4-5,7-8,10-11H2,1-3H3/t15-,16+,17+,18+,19+,20+/m1/s1

InChI key

XWALNWXLMVGSFR-HLXURNFRSA-N

Gene Information

human ... AR(367)

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General description

17β-hydroxy-17-methylandrosta-1,4-dien-3-one is an androgenic anabolic steroid.

Application

17β-hydroxy-17-methylandrosta-1,4-dien-3-one may be used as a reference standard in the determination of 17β-hydroxy-17-methylandrosta-1,4-dien-3-one in urine samples, using by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Comparative study of matrices for their use in the rapid screening of anabolic steroids by matrix?assisted laser desorption/ionisation time?of?flight mass spectrometry
Galesio.M, et al.
Rapid Communications in Mass Spectrometry, 23, 1783-1791 (2009)
Oscar J Pozo et al.
Drug testing and analysis, 1(11-12), 554-567 (2010-04-01)
Anabolic steroids are among the most frequently detected compounds in doping analysis. They are extensively metabolized and therefore an in-depth knowledge about steroid metabolism is needed. In this study, a liquid chromatography tandem mass spectometry (LC-MS/MS) method based on a
Stephanie Mosler et al.
Archives of toxicology, 86(1), 109-119 (2011-08-06)
There is increasing evidence that the biological activity of myostatin (MSTN), a negative regulator of muscle growth, is affected by training but also anabolic steroids. In this study, we analyzed the effects of the frequently abused anabolic steroid methandienone (Md)
Andy Zöllner et al.
Biological chemistry, 391(1), 119-127 (2009-11-19)
Anabolic-androgenic steroids are some of the most frequently misused drugs in human sports. Recently, a previously unknown urinary metabolite of metandienone, 17beta-hydroxymethyl-17 alpha-methyl-18-norandrosta-1,4,13-trien-3-one (20OH-NorMD), was discovered via LC-MS/MS and GC-MS. This metabolite was reported to be detected in urine samples
Linda L Ahonen et al.
Rapid communications in mass spectrometry : RCM, 24(7), 958-964 (2010-03-09)
We examined the feasibility of capillary liquid chromatography/microchip atmospheric pressure photoionization tandem mass spectrometry (capLC/microAPPI-MS/MS) for the analysis of anabolic steroids in human urine. The urine samples were pretreated by enzymatic hydrolysis (with beta-glucuronidase from Helix pomatia), and the compounds

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