68923

Esculetin

analytical standard

• Sinónimos: 6,7-Dihydroxycoumarin, Cichorigenin, Esculetin
• Fórmula empírica (notación de Hill): C₉H₆O₄
• Número de CAS: 305-01-1
• Peso molecular: 178.14
• Beilstein: 152788
• Número CE: 206-161-5
• Número MDL: MFCD00006874
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 329761226
• NACRES: NA.24

Propiedades

• grado: analytical standard
• Nivel de calidad: 100
• Ensayo: ≥97.5% (HPLC); 97.5-102.5% (NT)
• caducidad: limited shelf life, expiry date on the label
• mp: 271-273 °C (lit.)
• Formato: neat
• cadena SMILES: Oc1cc2OC(=O)C=Cc2cc1O
• InChI: 1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H
• Clave InChI: ILEDWLMCKZNDJK-UHFFFAOYSA-N

Descripción

Descripción general

Esculetin is a derivative of coumarin, found in various plant species including Cichorium intybus (chicory), Bougainvillea spectabilis, Artemisia capillaris, etc and leaves of Citrus limonia (Rutaceae), Ceratostigma willmottianum, etc. It exhibits multiple pharmacological activities and is found to be a potent inhibitor of cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, catechol-O-methyl transferase, NADPH oxidase and xanthine oxidase enzymes.

Aplicación

Esculetin may be used as an analytical reference standard for the determination of the analyte in biological and water samples by chromatography-based techniques. It may also be used as a standard in the quantification of the analyte in traditional herbal medicines by solid-phase extraction and micellar electrokinetic capillary methods, respectively.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable