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64306
S-Methyl methanethiosulfonate
purum, ≥98.0% (GC)
Sinónimos:
S-Methyl thiomethanesulfonate, MMTS
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1 ML
US$ 59,10
10 ML
US$ 282,00
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1 ML
US$ 59,10
10 ML
US$ 282,00
About This Item
Fórmula lineal:
CH3SO2SCH3
Número de CAS:
Peso molecular:
126.20
Beilstein/REAXYS Number:
1446059
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Productos recomendados
grade
purum
Quality Level
assay
≥98.0% (GC)
refractive index
n20/D 1.513 (lit.)
n20/D 1.513
bp
69-71 °C/0.4 mmHg (lit.)
solubility
chloroform: 750mg + 5 ml Chloroform mg/mL, colorless to light greenish-yellow
density
1.337 g/mL at 20 °C
1.337 g/mL at 25 °C (lit.)
functional group
disulfide
storage temp.
2-8°C
SMILES string
CSS(C)(=O)=O
InChI
1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3
InChI key
XYONNSVDNIRXKZ-UHFFFAOYSA-N
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Application
- Modification of Thiol Enzymes: S-methyl methanethiosulfonate (MMTS) offers a unique method for the modification of thiol enzymes and redox-regulated proteins, providing potential applications in biochemical research focused on enzyme regulation and redox biology (Makarov et al., 2019).
- Sensor Development for Protease Activity: S-methyl methanethiosulfonate is used as a blocking reagent on the structural transitions of papain-like cysteine proteases, which supports its utility in sensor development, allowing for the detection and analysis of protease activity in various biological processes (Markovic et al., 2023).
- Agricultural Pathogen Control: Research evaluating S-methyl methanethiosulfonate as a late blight inhibitor highlights its potential as a broad-range toxin against plant pathogens, suggesting applications in agriculture for the management of crop diseases (Joller et al., 2020).
Caution
may discolor to yellow on storage
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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S-Methyl methanethiosulfonate (MMTS) is a reagent used to trap the natural thiol-disulfide state of the proteins. The efficiency of trapping mixed disulfides in vivo has been found to be higher for MMTS than for the more commonly used N-ethylmaleimide. MMTS
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Thiosulfinates (TSs) have been implicated as a principle source of the antiplatelet property of raw onion and garlic juice. The in vitro responses of human platelets to dosages of four TSs were measured using whole blood aggregometry and compared by
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What is the solubility of Product 64306, S-Methyl methanethiosulfonate?
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Product 64306, S-Methyl methanethiosulfonate, is practically insoluble in water. It is soluble in methylene chloride. Several references do report that S-Methyl methanethiosulfonate is soluble in isopropanol at a 200mM concentration. References are provided below: 1. Yan, W., et al., "Quantitative Proteomic Analysis to Profile Dynamic Changes in the Spatial Distribution of Cellular Proteins", in Methods in Molecular Biology, Vol. 432: Organelle Proteomics, pp. 389-401 (Humana Press, 2008).2. Sadowski, P.G., et al., Quantitative proteomic approach to study subcellular localization of membrane proteins. Nature Protocols, 1, 1778-1789 (2006).
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