MABC292

Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD

clone 1.2, 1 mg/mL, from mouse

• Sinónimos: Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2, PSK2, Prostate-derived STE20-like kinase 2, Thousand and one amino acid protein kinase 1, TAOK1, hTAOK1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: 1.2, monoclonal
• reactividad de especies: human
• concentración: 1 mg/mL
• técnicas: western blot: suitable
• isotipo: IgG2bκ
• Nº de acceso NCBI: NP_065842
• Nº de acceso UniProt: Q7L7X3
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TAOK1(57551)

Descripción

Descripción general

TAOK1 , also known as Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2/PSK2, Prostate-derived STE20-like kinase 2, or Thousand and one amino acid protein kinase 1, TAOK1/hTAOK1, and encoded by the gene TAOK1/KIAA1361/MAP3K16/MARKK, is an important serine/threonine protein kinase involved in a variety of processes including p38/MAPK14 stress responses, DNA damage responses and cytoskeleton stability. TAOK1 also acts as regulator of apoptosis and controls the morphological changes associated with apoptosis including cell contraction, membrane blebbing and apoptotic body formation. TAOK1 is expressed in many tissues but highly expressed in testis as well as brain, colon and muscle. TAOK1 is localized to the cytoplasm and a target for caspase-3 as well as SPRED1 a regulator of the MAP kinase cascade.

Inmunógeno

Epitope: C-terminus

Linear peptide corresponding to the C-terminus of human TAOK1.

Aplicación

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD is validated for use in Western Blotting for the detection of TAOK1 (long isoform).

Western Blotting Analysis: A representative lot detected TAOK1 in HeLa cell lysate, but not in TAOK1 siRNA transfected HeLa cell lysate (Prof. Viji Draviam, University of Cambridge).

Calidad

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected TAOK1 in 10 µg of HeLa cell lysate.

Descripción de destino

~116 kDa observed

Forma física

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable