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MAB5200

Sigma-Aldrich

Anti-Synaptotagmin I Antibody

Chemicon®, from mouse

Sinónimos:

p65, Syt1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

monoclonal

species reactivity

frog, bovine, chicken, rabbit, rat, shark, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SYT1(6857)

Specificity

Synaptotagmin 1, also known as p65. By Western blot MAB5200 reacts with a single protein with a molecular weight of approximately 65 kDa. MAB5200 has not been epitope mapped.

Immunogen

Rat brain synaptotagmin.

Application

Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This Anti-Synaptotagmin I Antibody is validated for use in IP, WB, IC for the detection of Synaptotagmin I.
Western blot: 5 μg/mL (colormetric) Immunocytochemistry

Immunoprecipitation

Optimal working dilutions and protocols must be determined by the end user.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS with 50% glycerol and 0.09% sodium azide.

Storage and Stability

Maintain at -20°C in undiluted aliquots up to 12 months.Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Shadab Batool et al.
Cells, 10(12) (2021-12-25)
The perturbation of nicotinic cholinergic receptors is thought to underlie many neurodegenerative and neuropsychiatric disorders, such as Alzheimer's and schizophrenia. We previously identified that the tumor suppressor gene, MEN1, regulates both the expression and synaptic targeting of α7 nAChRs in
Jian Zhou et al.
The international journal of neuropsychopharmacology, 19(1) (2015-09-14)
While stressful events are recognized as an important cause of major depressive disorder, some individuals exposed to life stressors maintain normal psychological functioning. The molecular mechanism(s) underlying this phenomenon remain unclear. Abnormal transmission and plasticity of hippocampal synapses have been
Chang Liu et al.
The Journal of biological chemistry, 291(15), 8173-8188 (2016-02-11)
Alternative splicing generates multiple isoforms of the microtubule-associated protein Tau, but little is known about their specific function. In the adult mouse brain, three Tau isoforms are expressed that contain either 0, 1, or 2 N-terminal inserts (0N, 1N, and
Shadab Batool et al.
Cells, 10(5) (2021-06-03)
Menin, a product of MEN1 (multiple endocrine neoplasia type 1) gene is an important regulator of tissue development and maintenance; its perturbation results in multiple tumors-primarily of the endocrine tissue. Despite its abundance in the developing central nervous system (CNS)
Giota Tsotsokou et al.
International journal of molecular sciences, 25(13) (2024-07-13)
Fragile X syndrome (FXS) is an intellectual developmental disorder characterized, inter alia, by deficits in the short-term processing of neural information, such as sensory processing and working memory. The primary cause of FXS is the loss of fragile X messenger

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