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EZRMCP2

Millipore

Rat/Mouse C-Peptide 2 ELISA Kit

measures and quantifies C-Peptide 2 levels in 20 μL serum or plasma

Sinónimos:

C-Peptide 2

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About This Item

UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Rat/Mouse C-Peptide 2 ELISA, This Rat/Mouse C-Peptide 2 ELISA is used to measure & quantify C-Peptide 2 levels in Metabolism & Endocrine & Neuroscience research.

Quality Level

species reactivity

mouse, rat

packaging

kit of 1 × 96 wells

parameter

20 μL sample volume (4hr assay)

assay range

accuracy: 86-87%
(Mouse Serum)

accuracy: 88-92%
(Rat Serum)

accuracy: 93-95%
(Rat Plasma)

linearity: 86-108%
standard curve range: 25-1600 pM

technique(s)

ELISA: suitable

input

sample type plasma (K2 EDTA)
sample type serum

application(s)

research use

detection method

colorimetric (450nm/590nm)

shipped in

wet ice

storage temp.

2-8°C

General description

Measurement of C-peptide indicates the pancreatic β-cell function. Compared to endogenous insulin this protein is secreted at a more constant rate and for an extended time. Detection of C-peptide levels helps in diabetes diagnosis and management. The levels of C-peptide determine the type of diabetes and the duration of the disease.

Application

Rat/Mouse C-Peptide 2 ELISA has been used in in vivo experiments to determine the C-peptide levels in mice blood, sera, and plasma.

Features and Benefits

Each kit is sufficient to measure 39 unknown samples in duplicate.

Disclaimer

For research use only. Not for use in diagnostic procedures.

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Warning

hcodes

Hazard Classifications

Met. Corr. 1 - Skin Sens. 1

Storage Class

8A - Combustible corrosive hazardous materials


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Emma Leighton et al.
Diabetes therapy : research, treatment and education of diabetes and related disorders, 8(3), 475-487 (2017-05-10)
C-peptide is a widely used measure of pancreatic beta cell function. It is produced in equimolar amounts to endogenous insulin but is excreted at a more constant rate over a longer time. Methods of estimation include urinary and unstimulated and
Jean Franciesco Vettorazzi et al.
Scientific reports, 7(1), 14876-14876 (2017-11-03)
Disruption of insulin secretion and clearance both contribute to obesity-induced hyperinsulinemia, though reduced insulin clearance seems to be the main factor. The liver is the major site for insulin degradation, a process mainly coordinated by the insulin-degrading enzyme (IDE). The
Binhai Ren et al.
The journal of gene medicine, 20(5), e3017-e3017 (2018-03-27)
Gene therapy is one treatment that may ultimately cure type 1 diabetes. We have previously shown that the introduction of furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes resulted in the reversal of diabetes and
Samraa H Abdel-Kawi et al.
Stem cells international, 2022, 6342594-6342594 (2022-04-23)
Stem cell transplantation is a promising therapeutic technique for the treatment of a variety of diseases; nevertheless, stem cell therapy may not always work as well as it could. The goal of this study was to test the hypothesis that
Hana Vakili et al.
The Journal of clinical investigation, 124(11), 5002-5012 (2014-10-09)
Levels of pituitary growth hormone (GH), a metabolic homeostatic factor with strong lipolytic activity, are decreased in obese individuals. GH declines prior to the onset of weight gain in response to excess caloric intake and hyperinsulinemia; however, the mechanism by

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