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Merck

LM1601

Avanti

17:1 Lyso PC

Avanti Research - A Croda Brand LM1601, methanol solution

Sinónimos:

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphocholine

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About This Item

Fórmula empírica (notación de Hill):
C25H50NO7P
Número de CAS:
Peso molecular:
507.64
UNSPSC Code:
12352211
NACRES:
NA.25

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1601-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand LM1601

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O

Categorías relacionadas

General description

Lysophosphatidylcholine (LPC) is a polar lipid, localized to the cell membranes of oxidized lipoproteins.

Application

17:1 Lyso PC has been used as an LIPID MAPS internal standard for lipid extraction from serum and quantification in liquid chromatography mass-spectrometry (LC-MS) analysis.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) is a bioactive molecule involved in various biological processes such as vascular reproduction, development and myelination. It is associated to the progression of atherosclerosis, with findings of high concentration of LPC in the lesions/plaques. Higher levels of LPC are also found in oxidatively damaged low-density lipoprotein (oxLDL) indicating cardiovascular disease. LPC is known to be implicated in neuronal diseases and cancer.

Packaging

2 mL Amber Glass Sealed Ampule (LM1601-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


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A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
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Journal of Lipid Research, 52(12), 2314-2322 (2011)
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This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to

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