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860510P

Avanti

C10 Ceramide (d18:1/10:0)

Avanti Research™ - A Croda Brand 860510P, powder

Sinónimos:

N-decanoyl-D-erythro-sphingosine

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5 MG
US$ 147,00

US$ 147,00

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5 MG
US$ 147,00

About This Item

Fórmula empírica (notación de Hill):
C28H55NO3
Número de CAS:
111122-57-7
Peso molecular:
453.74
Número MDL:
MFCD02259134
Código UNSPSC:
12352211
NACRES:
NA.25

US$ 147,00

PRECIOS SIN IMPUESTOS NACIONALES
Check Cart for Availability
Solicitar un pedido a granel

Formulario

powder

envase

pkg of 1 × 5 mg (860510P-5mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 860510P

tipo de lípido

sphingolipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1

Clave InChI

FDWVAQFAMZLCAX-NBNLIBPQSA-N

Descripción general

C10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.[1]

Aplicación

C10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:
  • as an internal standard in galactocerebrosidase (GALC) assay[2]
  • to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines[3]
  • to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length[1]

Acciones bioquímicas o fisiológicas

Ceramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.[4]

Envase

5 mL Amber Glass Screw Cap Vial (860510P-5mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Joseph J Orsini et al.
Clinical biochemistry, 42(9), 877-884 (2009-03-26)
The aim of this study was to develop a newborn screening algorithm for Krabbe disease. We measured the galactocerebrosidase activity of 139,074 anonymous newborns, 56 known carriers, and 16 Krabbe patients using a tandem mass spectrometry method. The activities were
Michael A Rogers et al.
Food science & nutrition, 5(3), 579-587 (2017-06-03)
Short-chain ceramides, such as N-acetoyl-d-erythro-sphingosine (C2), have a remarkable ability to structure edible oils, such as canola oil, into self-standing organogels without any added saturated or trans fats. These short-chain ceramides are ubiquitously found in foods ranging from eggs to
Fernando Dupuy et al.
Chemistry and physics of lipids, 165(6), 615-629 (2012-07-12)
The organization of lipids within membranes strongly depends on the interaction with other lipid and protein molecules. Sphingolipids comprise a structurally diverse family, the ceramides being some of the simplest members. Although small chemical modifications of ceramide structure, such as
Meenu N Perera et al.
Chemistry and physics of lipids, 194, 110-116 (2015-09-27)
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity is unexpected considering that ceramide
Zhixing Wang et al.
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
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