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Merck

840475C

Avanti

18:1 (Δ9-Cis) PG

Avanti Research - A Croda Brand

Sinónimos:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))

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25 MG
US$ 130,00
200 MG
US$ 375,00
500 MG
US$ 637,00

US$ 130,00


Fecha estimada de envío15 de abril de 2025


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25 MG
US$ 130,00
200 MG
US$ 375,00
500 MG
US$ 637,00

About This Item

Fórmula empírica (notación de Hill):
C42H78O10PNa
Número de CAS:
Peso molecular:
797.03
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25

US$ 130,00


Fecha estimada de envío15 de abril de 2025


Solicitar un pedido a granel

description

1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform solution

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840475C-25mg)
pkg of 2 × 4 mL (840475C-200mg)
pkg of 5 × 4 mL (840475C-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

10 mg/mL (840475C-25mg)
25 mg/mL (840475C-200mg)
25 mg/mL (840475C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C42H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b19-17-,20-18-;/t39?,40-;/m

InChI key

IUVFCFQZFCOKRC-IPKKNMRRSA-M

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol.[1] It is found at high levels in the membranes of all cells and at low levels in fat stores.[2] 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.[3]

Application


  • Probing the extended lipid anchorage with cytochrome c and liposomes containing diacylphosphatidylglycerol lipids.: This study investigates the interactions of cytochrome c with liposomes containing diacylphosphatidylglycerol (PG) lipids, including 18:1 (Δ9-Cis) PG. The research provides insights into the lipid anchorage and membrane dynamics, which are crucial for understanding cellular processes and developing biotechnological applications involving lipid-protein interactions (Abbott et al., 2018).

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.[2]

Packaging

5 mL Clear Glass Sealed Ampule (840475C-200mg)
5 mL Clear Glass Sealed Ampule (840475C-25mg)
5 mL Clear Glass Sealed Ampule (840475C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Membrane Structure and Dynamics
Cell Biology, 227- 239 (2017)
Lipids
Medical Biochemistry, 99- 119 (2017)
Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment
Zhang Z, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(7), 1242- 1253 (2017)
Md Zahidul Islam et al.
Langmuir : the ACS journal of surfaces and colloids, 33(9), 2433-2443 (2017-02-07)
The translocation of cell-penetrating peptides (CPPs) through plasma membranes of living cells is an important physiological phenomenon in biomembranes. To reveal the mechanism underlying the translocation of a CPP, transportan 10 (TP10), through lipid bilayers, we examined the effects of
Mariya Chavarha et al.
Biophysical journal, 104(3), 594-603 (2013-02-28)
The hydrophobic surfactant proteins, SP-B and SP-C, greatly accelerate the adsorption of the surfactant lipids to an air/water interface. Previous studies of factors that affect curvature suggest that vesicles may adsorb via a rate-limiting structure with prominent negative curvature, in

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