777692

(1,10-Phenanthroline)(trifluoromethyl)copper(I)

90%

• Sinónimos: Trifluoromethylator^®
• Fórmula empírica (notación de Hill): C₁₃H₈CuF₃N₂
• Número de CAS: 1300746-79-5
• Peso molecular: 312.76
• Número MDL: MFCD19690901
• Código UNSPSC: 12352101
• ID de la sustancia en PubChem: 329767921
• NACRES: NA.22

Propiedades

• Ensayo: 90%
• Formulario: solid
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C12H8N2.CF3.Cu/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1;2-1(3)4;/h1-8H;;
• Clave InChI: CUQZQRIIFNWQSJ-UHFFFAOYSA-N

Descripción

Descripción general

(1,10-Phenanthroline)(trifluoromethyl)copper(I) [(Phen)Cu-CF₃] can be prepared by treating [CuOt-Bu]₄ with 1,10-phenanthroline, followed by the addition of (trifluoromethyl)trimethylsilane (CF₃TMS). It is an easily handled, thermally stable, single-component reagent.[1]

Aplicación

Trifluoromethylator, A New Arene Trifluoromethylation Reagent: (Phen)Cu-CF3

(Phen)Cu-CF₃ can be used as a reagent for the trifluoromethylation of aryl iodides. Electron-rich and electron-deficient iodoarenes, as well as sterically-hindered iodoarenes, react in high yield under mild conditions. Electrophilic functional groups, including aldehydes, nitroarenes, ketones, and esters are tolerated. The substrate scope of this reagent is broad and the reagent has wide applicability for trifluoromethylation reactions.[1]
It can also be used in the oxidative trifluoromethylation of organoboron reagents, and terminal alkynes through C-H activation.[2]

Información legal

Trifluoromethylator is a registered trademark of Catylix, Inc

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302 + H312,H315,H319
• Consejos de prudencia: P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 - P332 + P313
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable