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710806

Sigma-Aldrich

18-Hydroxycorticosterone

97% (CP)

Sinónimos:

4-Pregnene-11β,18,21-triol-3,20-dione

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About This Item

Fórmula empírica (notación de Hill):
C21H30O5
Número de CAS:
561-65-9
Peso molecular:
362.46
Beilstein:
2631066
Número CE:
209-221-9
Número MDL:
MFCD00042685
Código UNSPSC:
12352211
ID de la sustancia en PubChem:
329763011
NACRES:
NA.24

Nivel de calidad

200

Ensayo

97% (CP)

Formulario

powder

técnicas

mass spectrometry (MS): suitable

temp. de almacenamiento

−20°C

cadena SMILES

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(CO)[C@@]3([H])CC[C@]4([H])C(CO)=O)=C1

InChI

1S/C21H30O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,14-17,19,22-23,25H,2-7,9-11H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

Clave InChI

HFSXHZZDNDGLQN-ZVIOFETBSA-N

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This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
To best serve customer requests, each order is packaged and shipped on demand approximately 2 weeks after receipt of an order. If you have questions regarding availability and price, please contact the Stable Isotope Customer Service Group at 937-859-1808 (1-800-448-9760 for US & Canada) or email us at [email protected].

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MBBD5665
MBBD6898
MBBD6117
MBBD1895
MBBC7480

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Mei-Chuan Chen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 801(2), 347-353 (2004-01-31)
The analysis of corticosterone in mouse blood serum (metabolic-stress experiment) and 17-hydroxycorticosterone in human urine (exercise-stress experiment) samples by means of capillary electrophoresis/UV absorbance in conjunction with online sample concentration techniques is described. The use of normal MEKC had an
M Peter et al.
The Journal of clinical endocrinology and metabolism, 80(5), 1622-1627 (1995-05-01)
Aldosterone (Aldo), the most potent mineralocorticoid, is synthesized in the adrenal zona glomerulosa, requiring 11 beta-hydroxylation of 11-deoxycorticosterone (DOC) to form corticosterone (B), hydroxylation at position C18 to form 18-hydroxycorticosterone (18-OHB), and finally oxidation at position C18. There is a
C E Gomez-Sanchez et al.
The Journal of clinical endocrinology and metabolism, 67(2), 322-326 (1988-08-01)
The human adrenal gland can metabolize cortisol to yield steroids oxygenated at the 18 position in a series of reactions similar to those by which corticosterone is converted to 18-hydroxycorticosterone and aldosterone and perhaps catalyzed by the same enzyme. These
Paolo Mulatero et al.
The Journal of clinical endocrinology and metabolism, 97(3), 881-889 (2012-01-13)
Diagnosis of primary aldosteronism (PA) is made by screening, confirmation testing, and subtype diagnosis (computed tomography scan and adrenal vein sampling). However, some tests are costly and unavailable in most hospitals. The aim of the study was to evaluate the
Colin Patrick Cantwell et al.
Journal of computer assisted tomography, 32(5), 738-744 (2008-10-03)
To compare low-radiation dose non-enhanced fluorine 18 fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET)/computed tomography (CT) (NE-PET/CT), contrast-enhanced fluorine 18 fluorodeoxyglucose PET/CT (CE-PET/CT), and gadolinium-enhanced liver magnetic resonance imaging (MRI) for the detection and characterization of liver lesions in patients
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