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Merck

655422

Sigma-Aldrich

QuadraPure® TU

macroporous, 400-600 μm particle size

Sinónimos:

QuadraPure® Thiourea

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About This Item

MDL number:
UNSPSC Code:
12163800
PubChem Substance ID:
NACRES:
NA.22

reaction suitability

reagent type: catalyst
reagent type: chelator

particle size

400-600 μm

General description

QuadraPure® TU is a thiourea-based metal scavenger resin that can be used to prevent metal contamination that occurs during pharmaceutical or fine chemical processing.

Application

Metal Scavenger: Pd, Pt, Ru, Rh, Au, Ag, Cu, Hg, Pb, Cd, Ni, Co, Fe, V, Zn
QuadraPure® TU has been used to remove color from the solution due to leaching of copper species during the copper(I)-mediated 1,2,3-triazole formation via [3+2] cycloaddition of acetylenic compounds with azides. It has also been used as a modifier for carbon pastes to develop QuadraPure® TU residue functionalized resin-modified carbon paste electrode (“TUR-CPE”) for the determination of Pb(II) ions.
Other applications include the removal of metal ions like copper and palladium that leach out during continuous flow coupling reactions.

Legal Information

QuadraPure is a registered trademark of Johnson Matthey Finland Oy

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análisis (COA)

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Continuous flow ligand-free Heck reactions using monolithic Pd [0] nanoparticles.
Nikbin N, et al.
Organic Process Research & Development, 11(3), 458-462 (2007)
Sebastian Wesselbaum et al.
Angewandte Chemie (International ed. in English), 51(34), 8585-8588 (2012-07-19)
Dual role for CO(2): Pure formic acid can be obtained continuously by hydrogenation of CO(2) in a single processing unit. An immobilized ruthenium organometallic catalyst and a nonvolatile base in an ionic liquid (IL) are combined with supercritical CO(2) as
Michael J. Girgis, et al.
Organic Process Research & Development, 12, 1209-1217 (2008)
Continuous flow coupling and decarboxylation reactions promoted by copper tubing.
Zhang Y, et al.
Organic Letters, 13(2), 280-283 (2010)
Paolo Tosatti et al.
The Journal of organic chemistry, 76(13), 5495-5501 (2011-05-14)
The sequential use of Cu-catalyzed asymmetric allylic alkylation, olefin cross-metathesis, and Ir-catalyzed asymmetric allylic amination allows the concise, stereodivergent synthesis of complex chiral amines with complete regiocontrol and good diastereoselectivity, exemplified by the synthesis of a pair of diastereoisomeric unnatural

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