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Documentos

55088

Sigma-Aldrich

8-Hydroxy-2-quinolinecarboxylic acid

≥98.0% (HPLC)

Sinónimos:

8-Hydroxyquinaldic acid

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About This Item

Fórmula empírica (notación de Hill):
C10H7NO3
Número de CAS:
1571-30-8
Peso molecular:
189.17
Beilstein/REAXYS Number:
146082
MDL number:
MFCD00168972
UNSPSC Code:
12352100
PubChem Substance ID:
57651493
NACRES:
NA.22

assay

≥98.0% (HPLC)

form

solid

SMILES string

OC(=O)c1ccc2cccc(O)c2n1

InChI

1S/C10H7NO3/c12-8-3-1-2-6-4-5-7(10(13)14)11-9(6)8/h1-5,12H,(H,13,14)

InChI key

UHBIKXOBLZWFKM-UHFFFAOYSA-N

Categorías relacionadas

General description

8-Hydroxy-2-quinolinecarboxylic acid (8HQC) is a tridentate chelating agent. It reacts with 2-aminophenol to form a benzoxazole derivative, which can undergo fluorescence quenching in water, making it a viable candidate for developing a probe for detecting water in aprotic organic solvents. The analysis of mid-IR and Raman spectra of 8HQC shows the presence of seven tautomers.

Application

8-Hydroxy-2-quinolinecarboxylic acid may be used in the preparation of bis (8-hydroxyquinoline-2-carboxylato-Κ3N,O,O′) cobalt (II) trihydrate.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

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Sigma-Aldrich

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Determination of water content in aprotic organic solvents using 8-hydroxyquinoline based fluorescent probe.
Kim JS, et al.
Bull. Korean Chem. Soc., 27(12), 2058-2058 (2006)
Bis (8-hydroxyquinoline-2-carboxylato-?3N,O,O') cobalt (II) trihydrate.
Okabe N and Muranishi Y.
Acta Crystallographica Section E, Structure Reports Online, 58(7), m352-m353 (2002)
Katarzyna Walczak et al.
Molecules (Basel, Switzerland), 25(7) (2020-04-09)
8-Hydroxyquinaldic acid, the end-metabolite of tryptophan, is well-known metal chelator; however, its role in humans, especially in cancer promotion and progression, has not been fully revealed. Importantly, 8-hydroxyquinaldic acid is the analog of kynurenic acid with evidenced antiproliferative activity towards
A combined experimental and theoretical study on 8-hydroxy-2-quinolinecarboxylic acid.
Badoglu S and Yurdakul S.
Optics and Spectroscopy, 116(2), 196-206 (2014)
Francesco Bellia et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 26(70), 16690-16705 (2020-07-07)
Metal dysregulation, oxidative stress, protein modification, and aggregation are factors strictly interrelated and associated with neurodegenerative pathologies. As such, all of these aspects represent valid targets to counteract neurodegeneration and, therefore, the development of metal-binding compounds with other properties to
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