Journal of the American Chemical Society, 139(10), 3851-3860 (2017-02-22)
Permeabilization of the outer mitochondrial membrane is an integral step in apoptosis. The resulting release of pro-apoptotic signaling proteins leads to cell destruction through activation of the cysteine-aspartic protease (caspase) cascade. However, the mechanism of outer mitochondrial membrane (OMM) permeabilization
Water science and technology : a journal of the International Association on Water Pollution Research, 44(5), 7-13 (2001-11-07)
This paper describes the ozone oxidation kinetics of 1-naphthalene (1 NS), 1,5-naphthalene (1,5NDS), and 3-nitrobenzene (3NBS) sulphonic acid. The presence of hydroxyl radicals and their effect on the overall rate of reaction was studied. Second order kinetic constants of direct
Science (New York, N.Y.), 327(5968), 986-990 (2010-02-20)
Cationic organic intermediates participate in a wide variety of useful synthetic transformations, but their high reactivity can render selectivity in competing pathways difficult to control. Here, we describe a strategy for inducing enantioselectivity in reactions of protio-iminium ions, wherein a
The discovery and SAR of a new series of substituted 8-arylquinoline PDE4 inhibitors are herein described. This work has led to the identification of several compounds with excellent in vitro and in vivo profiles, including a good therapeutic window of
We examined the degradation of amaranth, a representative azo dye, by Bjerkandera adusta Dec 1. The degradation products were analyzed by high performance liquid chromatography (HPLC), visible absorbance, and electrospray ionization time-of-flight mass spectroscopy (ESI-TOF-MS). At the primary culture stage
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