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Merck

178950

Sigma-Aldrich

Methanesulfonyl fluoride

98%

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About This Item

Fórmula lineal:
CH3SO2F
Número de CAS:
Peso molecular:
98.10
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

assay

98%

reaction suitability

reaction type: click chemistry

bp

123-124 °C (lit.)

density

1.427 g/mL at 25 °C (lit.)

SMILES string

CS(F)(=O)=O

InChI

1S/CH3FO2S/c1-5(2,3)4/h1H3

InChI key

KNWQLFOXPQZGPX-UHFFFAOYSA-N

General description

Methanesulfonyl fluoride is an anticholinesterase (antiChEs), used to treat Alzheimer′s disease. It is a thrombin inhibitor.

For use with

Referencia del producto
Descripción
Precios

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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D H Malin et al.
Neurobiology of aging, 12(2), 181-183 (1991-03-01)
In previous studies, 18-month-old rats have shown no significant retention 24 hours after the single acquisition trial in a one-trial discriminative reward learning task. In the present study, ten 18-month-old rats pretreated with 0.5 mg/kg MSF IP showed significantly better
Navid Jamali et al.
Reproductive sciences (Thousand Oaks, Calif.), 28(3), 683-692 (2020-11-04)
Endometriosis, as the leading cause of infertility, is attributed to oxidative stress, inflammation, and autophagy dysregulation. This study was conducted to evaluate the effect of quercetin and metformin, alone or in combination, on the ectopic and eutopic endometrial tissues in
M Zorko et al.
Biochemical pharmacology, 35(14), 2287-2296 (1986-07-15)
The binding of D-tubocurarine (TC) to acetylcholinesterase (AChE) was studied using different methods of enzyme kinetics. The main results are as follows. TC reversibly inhibits the hydrolysis of different substrates of AChE with three different inhibition constants (Ki1 = 7.0
P Masson et al.
Biochimica et biophysica acta, 869(3), 304-313 (1986-02-14)
In order to determine whether a structural modification at the active center of cholinesterase may alter the conformational stability of the enzyme we compared the urea-induced unfolding of the tetrameric form of non-inhibited and irreversibly inhibited human plasma cholinesterase (acylcholine
A W Snow et al.
Chemical research in toxicology, 1(6), 379-384 (1988-11-01)
The chemical reactivity and physical properties of methanesulfonyl fluoride (MSF) were quantitatively measured for direct comparison with those of isopropyl methylphosphonofluoridate (GB, sarin) and diisopropyl phosphorofluoridate (DFP). The chemistry involved reaction rate constant measurements of MSF hydrolysis and for reactions

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