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Documentos

114480

Sigma-Aldrich

Cresol Red sodium salt

indicator grade

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About This Item

Fórmula empírica (notación de Hill):
C21H17NaO5S
Número de CAS:
62625-29-0
Peso molecular:
404.41
EC Number:
263-654-8
MDL number:
MFCD00001618
UNSPSC Code:
12171500
PubChem Substance ID:
24847175
NACRES:
NA.47

grade

indicator grade

form

solid

mp

250 °C (dec.) (lit.)

solubility

H2O: 1 mg/mL

λmax

425 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].Cc1cc(ccc1O)\C(=C2/C=CC(=O)C(C)=C2)c3ccccc3S([O-])(=O)=O

InChI

1S/C21H18O5S.Na/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26;/h3-12,22H,1-2H3,(H,24,25,26);/q;+1/p-1/b21-16-;

InChI key

GBXGEGUVARLBPB-PLMZOXRSSA-M

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Application

Cresol Red has been used for checking the immobilized carbonic anhydrase-catalyzed reactions. It has also been used in the loading buffer for MHC (major histocompatibility complex) class I typing through PCR.

Biochem/physiol Actions

Cresol Red is used as a pH indicator.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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K Horie et al.
Analytical biochemistry, 137(1), 80-87 (1984-02-01)
A highly sensitive quantitative method was developed to detect protons released or taken up upon ligand binding. A small change in pH due to proton release or uptake was detected by measuring the difference in the absorbance of a pH
E Hodges et al.
Molecular pathology : MP, 50(3), 164-166 (1997-06-01)
Diagnostic immunoglobulin (Ig) polymerase chain reaction (PCR) clonality analyses need to be simple, reproducible, and rapid. Sucrose and cresol red (gel loading buffer reagents) were added to a routine IgH PCR reaction mix to obviate the need for adding gel
Paula C A Jerónimo et al.
The Analyst, 130(8), 1190-1197 (2005-07-16)
An optical biosensor based on immobilised carbonic anhydrase and its application to the determination of the anti-glaucoma agent acetazolamide by enzyme inhibition measurements, is described. The enzyme and a pH indicator dye, cresol red, were physically immobilised in overlapped sol-gel
[Fundamental studies on the measurement of urinary NAG and determination of the normal values for NAG activity in various age groups].
Y Iimura et al.
Rinsho byori. The Japanese journal of clinical pathology, 31(2), 179-184 (1983-02-01)
K Schilling et al.
Clinical chemistry, 39(2), 251-256 (1993-02-01)
If buffer/indicator systems are used as optical thermometers in multicuvettes, the temperature resolution is limited by errors of optical measurements produced mainly by variations of pathlength and blank transmittance of the wells. Theoretical and practical approaches show that, in multicuvettes
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