CTSB
cathepsin B
Sinónimos:
APPS, CPSB
Especie:
Human CTSB (1508), Mouse Ctsb (13030), Rat Ctsb (64529), domestic guinea pig Ctsb (100714169), naked mole-rat Ctsb (101709008), dog CTSB (486077), Horse CTSB (100060963), domestic cat CTSB (101084873), cow CTSB (281105), sheep CTSB (780470)
ID UniProtKB:
ID del gen:
- Human(1508) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(13030) cathepsin B
- Rat(64529) cathepsin B
- domestic guinea pig(100714169) cathepsin B
- naked mole-rat(101709008) cathepsin B
- dog(486077) cathepsin B
- Horse(100060963) cathepsin B
- domestic cat(101084873) cathepsin B
- cow(281105) cathepsin B
- sheep(780470) cathepsin B
- chicken(396329) cathepsin B
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Cathepsin B (Ab-1) Mouse mAb (CA10), lyophilized, clone CA10, Calbiochem®,
Reactividad de especies
bovine, human, porcine
Aplicación
Anti-Cathepsin B Antibody, clone 6I5D7, Rabbit Monoclonal, ,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
western blot
Anti-CTSB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Especie
human
Cathepsin B, Human Liver, Cathepsin B, Human Liver, CAS 9047-22-7, is a purified native cathepsin B from human liver, purified by affinity chromatography. Upregulated in many types of tumors.,
Especie
human
esiRNA
Small Molecule - Substrate
Referencia del producto
Descripción
Especie