747599

Boxed reaction: Buchwald-Hartwig in Lipshutz Surfactant

• UNSPSC Code: 12161600
• NACRES: NA.22

Properties

• form: solid
• reaction suitability: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst
• greener alternative product characteristics: Waste Prevention; Designing Safer Chemicals; Design for Energy Efficiency; Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• greener alternative category: , Aligned

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for catalytic efficiency. Find details here.

Application

This kit contains the reagents, catalyst, and solvent required to perform a Buchwald-Hartwig reaction in TPGS-750-M, a surfactant developed by the Lipshutz group as a greener alternative to organic solvents. This technology allows common metal-catalyzed reactions to be run under aqueous conditions, considerably reducing solvent waste. The components are pre-weighed in the appropriate amounts for a 1 mmol scale reaction.

Please refer to the attached Protocol for details.

Kit Components Also Available Separately

• 156671 Potassium tert-butoxide, reagent grade, ≥98% 180 mg
• 222380 Allylpalladium(II) chloride dimer, 98% 5 mg
• cBRIDP 8 mg
• 733857 DL-α-Tocopherol methoxypolyethylene glycol succinate solution, 2 wt. % in H₂O 1 mL

Safety Information

• Pictograms: GHS02,GHS05
• Signal Word: Danger
• Hazard Statements: H228,H252,H260,H314
• Precautionary Statements: P210 - P231 + P232 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Sol. 2 - Self-heat. 2 - Skin Corr. 1A - Water-react 1
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials