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128376

Sigma-Aldrich

4-Fluorobenzaldehyde

98%

Synonym(s):

p-Fluorobenzaldehyde

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10 G
$38.10
50 G
$99.50
250 G
$414.00

$38.10

Estimated to ship onMarch 28, 2025

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10 G
$38.10
50 G
$99.50
250 G
$414.00

About This Item

Linear Formula:
FC6H4CHO
CAS Number:
459-57-4
Molecular Weight:
124.11
Beilstein:
385857
EC Number:
207-293-6
MDL number:
MFCD00003378
UNSPSC Code:
12352100
PubChem Substance ID:
24847852
NACRES:
NA.22
form:
liquid
Assay:
98%

$38.10

Estimated to ship onMarch 28, 2025

Request a Bulk Order

Quality Level

100

Assay

98%

form

liquid

refractive index

n20/D 1.521 (lit.)

bp

181 °C/758 mmHg (lit.)

mp

−10 °C (lit.)

density

1.157 g/mL at 25 °C (lit.)

functional group

aldehyde
fluoro

SMILES string

[H]C(=O)c1ccc(F)cc1

InChI

1S/C7H5FO/c8-7-3-1-6(5-9)2-4-7/h1-5H

InChI key

UOQXIWFBQSVDPP-UHFFFAOYSA-N

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General description

4-Fluorobenzaldehyde, also known as p-Fluorobenzaldehyde is an organic compound often used in the condensation reactions for the synthesis of phenolic monomers. [1]

Application

4-Fluorobenzaldehyde was used in the preparation of pyrazolopyridine UR-13756[2].

Signal Word

Warning

Hazard Statements

H226,H302,H319,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Flam. Liq. 3

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

132.8 °F - closed cup

Flash Point(C)

56 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW2569
0000263986
MKCT4363
MKCS9862
0000263986

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Abdul Hafeez et al.
Polymers, 11(9) (2019-09-22)
Bis-aldehyde monomers 4-(4'-formyl-phenoxy)benzaldehyde (3a), 3-methoxy-4-(4'-formyl-phenoxy)benzaldehyde (3b), and 3-ethoxy-4-(4'-formyl-phenoxy)benzaldehyde (3c) were synthesized by etherification of 4-fluorobenzaldehyde (1) with 4-hydroxybenzaldehyde (2a), 3-methoxy-4-hydroxybenzaldehyde (2b), and 3-ethoxy-4-hydroxybenzaldehyde (2c), respectively. Each monomer was polymerized with p-phenylenediamine and 4,4'-diaminodiphenyl ether to yield six poly(azomethine)s. Single crystal
Mark C Bagley et al.
Future medicinal chemistry, 2(2), 193-201 (2011-03-24)
UR-13756 is a potent and selective p38 mitogen-activated protein kinase (MAPK) inhibitor, reported to have good bioavailability and pharmacokinetic properties and, thus, is of potential use in the treatment of accelerated aging in Werner syndrome. Irradiation of 2-chloroacrylonitrile and methylhydrazine
Xuemei Tian et al.
Enzyme and microbial technology, 84, 32-40 (2016-02-02)
The first Novozym 435 lipase-catalyzed Morita-Baylis-Hillman (MBH) reaction with amides as co-catalyst was realized. Results showed that neither Novozym 435 nor amide can independently catalyze the reaction. This co-catalytic system that used a catalytic amount of Novozym 435 with a
Ana Margarida Araújo et al.
Archives of toxicology, 92(11), 3307-3323 (2018-09-27)
3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a well-known hepatotoxic drug. Although its toxicity has been thoroughly studied at high concentrations, there is still insufficient knowledge on possible alterations of cell function at subtoxic concentrations, which are in fact more representative concentrations of
Bin-Yu Wen et al.
Journal of Asian natural products research, 21(7), 702-715 (2019-01-01)
Desmosdumotin C (Des C), a natural product isolated from the roots of Desmos dumosus, has shown good antitumor activity. A three dimensional quantitative structure-activity relationship (QSAR) study using the comparative molecular field analysis (CoMFA) method was performed on 32 Des
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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