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1356632

USP

Ketoprofen

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-(3-Benzoylphenyl)propionic acid

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About This Item

Empirical Formula (Hill Notation):
C16H14O3
CAS Number:
22071-15-4
Molecular Weight:
254.28
MDL number:
MFCD00055790
UNSPSC Code:
41116107
PubChem Substance ID:
329750217
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ketoprofen

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketoprofen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Ketoprofen Capsules
  • Ketoprofen Extended-Release Capsules

Biochem/physiol Actions

Non-steroidal anti-inflammatory compound that is selective for COX-1.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

K2000000

Ketoprofen, European Pharmacopoeia (EP) Reference Standard

K2000010

Ketoprofen impurity A, European Pharmacopoeia (EP) Reference Standard

K2000015

Ketoprofen impurity C, European Pharmacopoeia (EP) Reference Standard

1356643

Ketoprofen Related Compound A, United States Pharmacopeia (USP) Reference Standard

1356563

Ketoprofen Related Compound D hydrochloride, United States Pharmacopeia (USP) Reference Standard

1356552

Ketoprofen Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP668

Ketoprofen, British Pharmacopoeia (BP) Reference Standard

BP667

Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

PHR2877

Ketoprofen Related Compound F, pharmaceutical secondary standard, certified reference material

PHR2955

Ketoprofen Related Compound D, pharmaceutical secondary standard, certified reference material

PHR3018

Ketoprofen Related Compound C, pharmaceutical secondary standard, certified reference material

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H301,H315,H319,H400

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fabíola Garavello Prezotti et al.
Carbohydrate polymers, 113, 286-295 (2014-09-27)
Gellan gum/pectin beads were prepared by ionotropic gelation, using Al(3+) as crosslinker. High yield (92.76%) and entrapment efficiency (52.22-88.78%) were reached. Beads exhibited high circularity (0.730-0.849) and size between 728.95 and 924.56 μm. Particle size and circularity was increased by
H Bagheri et al.
Drug safety, 22(5), 339-349 (2000-06-01)
The topical use of nonsteroidal anti-inflammatory drugs (NSAIDs), widely used for moderate acute and chronic painful conditions, is one of several strategies used to improve the tolerability profile of NSAIDs, particularly with regard to gastric and renal adverse effects. However
M Sugiura et al.
Contact dermatitis, 43(1), 16-19 (2000-07-21)
We report 4 cases of photocontact dermatitis due to ketoprofen, a non-steroidal anti-inflammatory drug derived from propionic acid. We carried out a skin biopsy to examine the amount of ketoprofen in the eruptive skin. We investigated the cross-reactions between tiaprofenic
Jodie Barden et al.
The Cochrane database of systematic reviews, (4)(4), CD007355-CD007355 (2009-10-13)
Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions. Dexketoprofen is the (S)-enantiomer, which is believed to confer analgesia. Theoretically dexketoprofen is expected to provide equivalent analgesia to ketoprofen at half the dose
F Jamali et al.
Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the
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