Skip to Content
Merck
All Photos(2)

Key Documents

View All Documentation

406902

Sigma-Aldrich

6-Mercaptopyridine-3-carboxylic acid

technical grade, 90%

Synonym(s):

6-Mercaptonicotinic acid

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C6H5NO2S
CAS Number:
92823-43-3
Molecular Weight:
155.17
MDL number:
MFCD00192261
UNSPSC Code:
12352100
PubChem Substance ID:
24865412
NACRES:
NA.22

grade

technical grade

Assay

90%

form

solid

mp

260-262 °C (dec.) (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc(S)nc1

InChI

1S/C6H5NO2S/c8-6(9)4-1-2-5(10)7-3-4/h1-3H,(H,7,10)(H,8,9)

InChI key

JWWGTYCXARQFOT-UHFFFAOYSA-N

General description

6-Mercaptopyridine-3-carboxylic acid (MPCA, 6-mercaptonicotinic acid, MNA) is a bifunctional ligand, made up of pyridine moiety containing carboxylic and mercapto group. The electrochemical properties of self-assembled monolayers (SAMs) of MNA on gold electrode have been described.

Application

6-Mercaptopyridine-3-carboxylic acid may be used in the following processes:
  • Fabrication of nanowell based sensors for the detection of improvised explosive devices (IEDs).
  • Functionalization of gold nanoparticles (AuNPs) for the highly sensitive and selective detection of Cd2+ in colorimetric assay.
  • Preparation of thiolated chitosans, which are thiolated biopolymers exhibiting mucoadhesive, enzyme inhibitory, and permeation enhancing properties.
  • Synthesis of Zinc(II) coordination polymers.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000358538
0000318935
0000358538
0000191025
0000205018

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Highly sensitive and specific determination of mercury (II) ion in water, food and cosmetic samples with an ELISA based on a novel monoclonal antibody.
Wang Y, et al.
Analytical and Bioanalytical Chemistry, 403(9), 2519-2528 (2012)
Pei She et al.
Analytica chimica acta, 906, 139-147 (2016-01-17)
An immunochromatographic test (ICT) strip was developed for ultrasensitive competitive immunoassay of Hg(2+). This strategy was achieved by combining the easy-operation and rapidity of ICT with the high sensitivity of surface-enhanced Raman scattering (SERS). Monoclonal antibody (mAb) against Hg(2+) and
Gioconda Millotti et al.
Biomacromolecules, 10(11), 3023-3027 (2009-10-14)
Thiolated chitosans are relatively new thiolated biopolymers exhibiting mucoadhesive, enzyme inhibitory, and permeation enhancing properties. A drawback, however, is their pH dependent reactivity. The aim of this study was therefore to develop a novel thiolated chitosan showing a non pH
Ying Xue et al.
The Analyst, 136(18), 3725-3730 (2011-08-02)
We have developed a colorimetric assay for the highly sensitive and selective detection of Cd(2+) using gold nanoparticles (AuNPs) cofunctionalized with 6-mercaptonicotinic acid (MNA) and L-Cysteine (L-Cys) through the formation of an Au-S bond. In the presence of Cd(2+), the
Electrochemical studies of 6-mercaptonicotinic acid monolayer on Au electrode.
Raj CR and Behera S.
Journal of Electroanalytical Chemistry, 581(1), 61-69 (2005)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service