219827
(S)-(−)-2-Hydroxyisocaproic acid
98%
Synonym(s):
2-Hydroxy-4-methylvaleric acid, L-2-Hydroxy-4-methylpentanoic acid, L-Leucic acid
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About This Item
Linear Formula:
(CH3)2CHCH2CH(OH)CO2H
CAS Number:
Molecular Weight:
132.16
EC Number:
MDL number:
UNSPSC Code:
51113400
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
form
powder
optical activity
[α]22/D −26.3°, c = 1 in 1 M NaOH
mp
78-80 °C (lit.)
functional group
carboxylic acid
hydroxyl
SMILES string
CC(C)C[C@H](O)C(O)=O
InChI
1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key
LVRFTAZAXQPQHI-YFKPBYRVSA-N
Related Categories
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Nature communications, 9(1), 3534-3534 (2018-09-01)
Reprogramming of the NRPS/PKS assembly line is an attractive method for the production of new bioactive molecules. However, it is usually hampered by the loss of intimate domain/module interactions required for the precise control of chain transfer and elongation reactions.
Charles H Lang et al.
American journal of physiology. Endocrinology and metabolism, 305(3), E416-E428 (2013-06-13)
Muscle disuse atrophy is observed routinely in patients recovering from traumatic injury and can be either generalized resulting from extended bed rest or localized resulting from single-limb immobilization. The present study addressed the hypothesis that a diet containing 5% α-hydroxyisocaproic
Fernanda U Fontella et al.
Metabolic brain disease, 17(1), 47-54 (2002-03-16)
In this study we investigated the in vitro effects of the metabolites accumulating in maple syrup urine disease on lipid peroxidation in brain of young rats. Chemiluminescence and thiobarbituric acid-reactive substances were measured in brain homogenates from 7- and 30-day-old
Antti A Mero et al.
Journal of the International Society of Sports Nutrition, 7, 1-1 (2010-01-07)
Alfa-Hydroxy-isocaproic acid (HICA) is an end product of leucine metabolism in human tissues such as muscle and connective tissue. According to the clinical and experimental studies, HICA can be considered as an anti-catabolic substance. The present study investigated the effects
2-Hydroxyisocaproic acid (HICA): a new potential topical antibacterial agent.
M Sakko et al.
International journal of antimicrobial agents, 39(6), 539-540 (2012-04-10)
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