LIGHTOX14

LightOx^™14

≥98% (HPLC)

• Empirical Formula (Hill Notation): C₂₃H₂₅NO₂
• CAS Number: 198696-03-6
• Molecular Weight: 347.45
• UNSPSC Code: 12352101
• NACRES: NA.22

Properties

• Assay: ≥98% (HPLC)
• form: powder
• storage temp.: 2-8°C

Description

Application

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

Biochem/physiol Actions

Strong ligand for retinoic acid receptor proteins

Features and Benefits

LightOx14 is a synthetic analogue of all-trans-retinoic acid (ATRA) that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx14 can be utilized to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Other Notes

Chemical Equivalency 1ea=1mg

Legal Information

LightOx is a trademark of LightOx Ltd.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable