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C8527

Sigma-Aldrich

Chlorhexidine dihydrochloride

≥98%

Synonym(s):

1,6-Bis(N5-[p-chlorophenyl]-N1-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide), Lisium

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About This Item

Empirical Formula (Hill Notation):
C22H30Cl2N10 · 2HCl
CAS Number:
3697-42-5
Molecular Weight:
578.37
EC Number:
223-026-6
MDL number:
MFCD00068998
UNSPSC Code:
12352100
PubChem Substance ID:
57654049
NACRES:
NA.22

Quality Level

100

Assay

≥98%

form

powder

storage temp.

2-8°C

SMILES string

Cl.Clc1ccc(NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)Nc2ccc(Cl)cc2)cc1

InChI

1S/C22H30Cl2N10.2ClH/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;;/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H

InChI key

WJLVQTJZDCGNJN-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Afshin Haraji et al.
Journal of orofacial pain, 27(3), 256-262 (2013-07-25)
To assess the effects of intra-alveolar application of chlorhexidine gel on the incidence of alveolar osteitis (dry socket) and the severity of postsurgical pain. A total of 160 impacted mandibular third molars were extracted in 80 patients enrolled in this
Rengin Attin et al.
Australian orthodontic journal, 29(1), 52-57 (2013-06-22)
The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in highlevel MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement. The subjects of this single-blinded clinical trial
Sissel Skovgaard et al.
The Journal of antimicrobial chemotherapy, 68(10), 2226-2233 (2013-06-07)
Chlorhexidine is used as a disinfectant to prevent surgical infections. Recently, studies have indicated that chlorhexidine usage has selected methicillin-resistant Staphylococcus aureus strains that are tolerant to chlorhexidine and that this may be related to the presence of the qacA/B-encoded
C M Martín-Navarro et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 251(9), 2111-2117 (2013-05-21)
Acanthamoeba is an opportunistic pathogen which is the causal agent of a sight-threatening ulceration of the cornea known as "Acanthamoeba keratitis" (AK) and, more rarely, an infection of the central nervous system called "granulomatous amoebic encephalitis" (GAE). The symptoms of
Maristela Dutra-Correa et al.
The journal of adhesive dentistry, 15(3), 287-292 (2013-04-06)
This study tested the hypothesis that 2% chlorhexidine (CHX) does not affect the 18-month clinical performance of two dentin adhesives, XP Bond (XPB) and XENO V (XEN). A total of 120 noncarious cervical lesions (NCCL) were selected and assigned to
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