Skip to Content
Merck
All Photos(1)

Key Documents

767654

Sigma-Aldrich

cis-Dichlorobis(dimethyl sulfoxide)platinum(II)

97%

Synonym(s):

cis-Dichlorobis(dimethylsulfoxido)platinum(II), Pt(DMSO)2Cl2

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C4H12Cl2O2PtS2
CAS Number:
Molecular Weight:
422.25
MDL number:
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

reaction suitability

core: platinum
reagent type: catalyst

mp

218-224 °C

SMILES string

Cl[Pt]Cl.CS(C)=O.CS(C)=O

InChI

1S/2C2H6OS.2ClH.Pt/c2*1-4(2)3;;;/h2*1-2H3;2*1H;/q;;;;+2/p-2

InChI key

KDADQDWVKZJTDQ-UHFFFAOYSA-L

General description

cis-Dichlorobis(dimethyl sulfoxide)platinum(II) is a platinum complex used as a catalyst in various chemical reactions, including the methylation of polyfluorinated aryl imines and methane oxidation. It is identified as an effective C-F activation precatalyst.

Application

cis-Dichlorobis(dimethyl sulfoxide)platinum(II) can be used as a:
  • Catalyst in the oleum-mediated (SO3-H2SO4) methane oxidation to form methyl bisulfate (MBS).
  • Precursor in the synthesis of cyclometalated complexes.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A W Konings et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 9(4), 553-562 (1993-07-01)
cDDP-resistant Ehrlich ascites tumour (EAT) cells (ER cells) were tested for cellular content of total glutathione, heat sensitivity, cDDP sensitivity and synergistic effects of a combined treatment of heat and chemotherapy. In comparison with the non-resistant EAT cells (EN) the
R S Dewoskin et al.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 9(4), 529-537 (1993-07-01)
The effects of hyperthermia (HY) on cisplatin (CDDP) nephrotoxicity and kidney metal concentrations were evaluated in female F344 rats. Rats were anaesthetized with a xylazine/ketamine mixture, heated on a water-bed for 1 h to an intraperitoneal temperature of 41.1 +/-
J M Bachaud et al.
Bulletin du cancer, 81(3), 212-218 (1994-03-01)
In order to enhance radiation effects in the treatment of unresectable Head and Neck squamous cell carcinoma, we initiated a phase I-II study in February 1991 with concomitant radiation and cisplatin in the treatment of resectable Head and Neck squamous
Synthesis, characterization, and photophysical properties of cyclometalated N-Heterocyclic carbene platinum (II) complexes
Mastrocinque F, et al.
Journal of Organometallic Chemistry, 880, 98-107 (2019)
H Nakagawa et al.
Journal of neuro-oncology, 16(1), 61-67 (1993-04-01)
The distribution of cis-diamminedichloroplatinum (CDDP) was studied in 23 patients undergoing surgical resection of brain tumors metastatic from lung cancer. CDDP (100 mg/m2) was administered intravenously (i.v.) or intra-arterially (IA) at the time of surgery, and various fluids and tissues

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service