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C8784

Sigma-Aldrich

Anti-Corticosterone antibody produced in rabbit

whole antiserum, lyophilized powder

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About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

technique(s)

radioimmunoassay: suitable (dextran coated charcoal 3H RIA)

storage temp.

2-8°C

target post-translational modification

unmodified

General description

Corticosterone is a steroid hormone produced mainly in the cortex of adrenal glands. It also known as the stress hormone and has a crucial role in enhancing and suppressing synaptic plasticity and memory processes.Rabbit anti-corticosterone antibody reacts specifically with corticosterone.

Immunogen

Corticosterone-21-Thyroglobulin

Application

Anti-corticosterone antibody can be used to measure total CORT level in serum using radioimmunoassay.

Physical form

The product is provided as a pre-diluted antiserum that has been lyophilized. Each vial contains no more than 20 mg Polyvinylpyrrolidone (PVP).

Reconstitution

Reconstitute with 5 mL buffer: 0.05 M Tris-HCl, pH 8.0, 0.1 M sodium chloride, 0.1% bovine serum albumin, and 0.1% sodium azide. Store this stock at −20 °C. Working dilution (1:10) to be discarded if unused within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Daniel A Warner et al.
Proceedings. Biological sciences, 274(1611), 883-890 (2007-01-26)
Life-history traits such as offspring size, number and sex ratio are affected by maternal feeding rates in many kinds of animals, but the consequences of variation in maternal diet quality (rather than quantity) are poorly understood. We manipulated dietary quality
Stéphane Martin et al.
PloS one, 4(3), e4714-e4714 (2009-03-24)
The stress hormone corticosterone has the ability both to enhance and suppress synaptic plasticity and learning and memory processes. However, until today there is very little known about the molecular mechanism that underlies the bidirectional effects of stress and corticosteroid
Noraine Salleh Hudin et al.
Ecology and evolution, 7(16), 6163-6171 (2017-09-02)
Several studies on birds have proposed that a lack of invertebrate prey in urbanized areas could be the main cause for generally lower levels of breeding success compared to rural habitats. Previous work on house sparrows Passer domesticus found that
Than J Boves et al.
Conservation physiology, 4(1), cow041-cow041 (2016-10-13)
In migratory species, breeding and non-breeding locations are geographically separate, yet the effects of conditions from one stage may carry over to affect a subsequent stage. Ideally, to understand the mechanisms and implications of 'carry-over effects', one would need to
Sabrina G V Dutra et al.
Neuroendocrinology, 111(1-2), 70-86 (2020-01-20)
Furosemide is a loop diuretic widely used in clinical practice for the treatment of oedema and hypertension. The aim of this study was to determine physiological and molecular changes in the hypothalamic-neurohypophysial system as a consequence of furosemide-induced sodium depletion.

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