Skip to Content
Merck
All Photos(4)

Documents

M8010

Sigma-Aldrich

N,N′-Dimethyl-9,9′-biacridinium dinitrate

Powder

Synonym(s):

9,9′-Bis(N-methylacridinium nitrate), Lucigenin

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C28H22N4O6
CAS Number:
Molecular Weight:
510.50
Beilstein:
3901768
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

N,N′-Dimethyl-9,9′-biacridinium dinitrate, used as chemiluminescent reagent

Quality Level

form

powder

mp

245-250 °C

solubility

acetic acid: 10 mg/mL

fluorescence

λex 319 nm; λem 384 nm (pH 9.0)
λex 360 nm; λem 449 nm (Reaction product)
λex 368 nm; λem 505 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[O-][N+]([O-])=O.[O-][N+]([O-])=O.C[n+]1c2ccccc2c(-c3c4ccccc4[n+](C)c5ccccc35)c6ccccc16

InChI

1S/C28H22N2.2NO3/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28;2*2-1(3)4/h3-18H,1-2H3;;/q+2;2*-1

InChI key

KNJDBYZZKAZQNG-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

N,N′-Dimethyl-9,9′-biacridinium dinitrate has been used in chemiluminescence assay to measure reactive oxygen species production and superoxide production.
Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen; it is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Feng-Lin Yen et al.
PloS one, 8(5), e63845-e63845 (2013-05-15)
Upregulation of intercellular adhesion molecule-1 (ICAM-1) involves adhesions between both circulating and resident leukocytes and the human lung epithelial cells during lung inflammatory reactions. We have previously demonstrated that curcumin-loaded polyvinylpyrrolidone nanoparticles (CURN) improve the anti-inflammatory and anti-oxidative properties of
Enhanced XOR activity in eNOS-deficient mice: effects on the nitrate-nitrite-NO pathway and ROS homeostasis
Peleli M, et al.
Free Radical Biology & Medicine, 99, 472-484 (2016)
Combination of cilostazol and probucol protected podocytes from lipopolysaccharide-induced injury by both anti-inflammatory and anti-oxidative mechanisms
He P, et al.
Journal of Nephrology, 30, 531-541 (2017)
Paula Denise Prince et al.
Redox biology, 11, 342-349 (2017-01-01)
This work investigated the capacity of (-)-epicatechin to prevent the renal damage induced by LPS administration in rats. Male Sprague Dawley rats were fed for 4 days a diet without or with supplementation with (-)-epicatechin (80mg/kg BW/d), and subsequently i.p.
John Elmerdahl Olsen et al.
BMC microbiology, 13, 67-67 (2013-03-28)
The importance of flagella and chemotaxis genes in host pathogen interaction in Salmonella enterica is mainly based on studies of the broad host range serovar, S. Typhimurium, while little is known on the importance in host specific and host adapted

Articles

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service