D9565
β-Defensin 1 human
≥98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)
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About This Item
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recombinant
expressed in E. coli
Assay
≥98% (HPLC and SDS-PAGE)
form
lyophilized powder (from 10 mM acetic acid)
mol wt
estimated mol wt 3.9 kDa
UniProt accession no.
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
fungi
viruses
Mode of action
cell wall synthesis | interferes
storage temp.
−20°C
Gene Information
human ... DEFB1(1672)
Amino Acid Sequence
Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]
General description
Chemical structure: peptide
Biochem/physiol Actions
A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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