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BCR096

Dibenzo[a,l]pyrene

BCR®, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C24H14
CAS Number:
191-30-0
Molecular Weight:
302.37
Beilstein:
2054068
MDL number:
MFCD00467035
UNSPSC Code:
41116107
PubChem Substance ID:
329774220
NACRES:
NA.24

grade

certified reference material

Agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

SMILES string

c1ccc2c(c1)cc3ccc4cccc5c6ccccc6c2c3c45

InChI

1S/C24H14/c1-2-8-18-16(6-1)14-17-13-12-15-7-5-11-20-19-9-3-4-10-21(19)24(18)23(17)22(15)20/h1-14H

InChI key

JNTHRSHGARDABO-UHFFFAOYSA-N

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Analysis Note

For more information please see:
BCR096

Legal Information

BCR is a registered trademark of European Commission

Pictograms

Health hazardCorrosion
GHS08,GHS05

Signal Word

Danger

Hazard Statements

H318,H341,H350

Hazard Classifications

Carc. 1B - Eye Dam. 1 - Muta. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Fredine T Lauer et al.
Journal of toxicology and environmental health. Part A, 76(1), 16-24 (2012-11-16)
Dibenzo[def,p]chrysene (DBC) is a potent environmental carcinogen in rodents, fish, and human cells examined in culture. There are numerous similarities between the patterns of cytochrome P-450 (P450) activation of DBC and its covalent binding to DNA and proteins with another
Lisbeth K Siddens et al.
Toxicology and applied pharmacology, 264(3), 377-386 (2012-09-01)
The polycyclic aromatic hydrocarbon (PAH), benzo[a]pyrene (BaP), was compared to dibenzo[def,p]chrysene (DBC) and combinations of three environmental PAH mixtures (coal tar, diesel particulate and cigarette smoke condensate) using a two stage, FVB/N mouse skin tumor model. DBC (4nmol) was most
George S Bailey et al.
Chemical research in toxicology, 22(7), 1264-1276 (2009-05-20)
Assessment of human cancer risk from animal carcinogen studies is severely limited by inadequate experimental data at environmentally relevant exposures and by procedures requiring modeled extrapolations many orders of magnitude below observable data. We used rainbow trout, an animal model
David J Castro et al.
Carcinogenesis, 30(2), 315-320 (2008-12-17)
The carcinogenic potential of dibenzo[a,l]pyrene (DBP) has been well characterized in numerous animal models. We have previously documented that a single dose of 15 mg/Kg DBP to pregnant mice late in gestation (GD 17) produces an aggressive T-cell lymphoma as
Kun-Ming Chen et al.
International journal of cancer, 133(6), 1300-1309 (2013-03-14)
We previously reported that dibenzo[a,l]pyrene (DB[a,l]P), the most potent known environmental carcinogen among polycyclic aromatic hydrocarbons (PAH) congeners, is carcinogenic in the oral tissues of mice. We have now developed a new mouse model which employs the oral application of
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