8.55052
Mca NovaTag® resin
Novabiochem®
Synonym(s):
N-Mca-NÆ-Fmoc-ethylenediamine MPB-AM resin
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About This Item
UNSPSC Code:
12352116
NACRES:
NA.22
Recommended Products
Quality Level
product line
NovaSyn® TG
Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
15-25°C
General description
Mca NovaTag resin is an ideal tool for the synthesis of FRET peptide substrates based on the 7-methoxycoumarin (Mca) and 2,4-dinitrophenyl(Dnp) fluorophore/quench pair. The resin pre-loaded with the Mca fluorophore can be used directly in Fmoc SPPS. Following peptide assembly, the Dnp group can be introduced using Fmoc-Lys(Dnp)-OH, to give after TFA cleavage the desired FRET peptide substrate.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Linkage
Replaces: 04-12-3902
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.20 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 % DVB 100 - 200 mesh
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.20 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 % DVB 100 - 200 mesh
Legal Information
NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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