PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Synonyms:
LYP, LYP1, LYP2, PEP, PTPN8
Species:
Human PTPN22 (26191), Mouse Ptpn22 (19260), Rat Ptpn22 (295338), Domestic Rabbit PTPN22 (100354293), naked mole-rat Ptpn22 (101711810), domestic cat PTPN22 (101099820), domestic guinea pig Ptpn22 (100717611), Zebrafish ptpn22 (565606), dog PTPN22 (483124), cow PTPN22 (518992) ...More
UniProtKB ID:
Gene ID:
- Human(26191) Summary: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009]
- Mouse(19260) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- Rat(295338) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- Domestic Rabbit(100354293) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- naked mole-rat(101711810) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- domestic cat(101099820) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- domestic guinea pig(100717611) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- Zebrafish(565606) protein tyrosine phosphatase, non-receptor type 22
- dog(483124) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- cow(518992) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- sheep(101119860) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
- chicken(772032) protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PTPN22 antibody produced in mouse, clone 1A6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-PTPN22 antibody produced in mouse, clone 4F6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PTPN22 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunohistochemistry
Anti-PTPN22 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Species Reactivity
human
Application
immunohistochemistry
Anti-PTPN22 Antibody, clone 3B3.1, culture supernatant, clone 3B3.1, from mouse,
Species Reactivity
human
Application
western blot