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P6801

Sigma-Aldrich

Sodium phosphonoformate tribasic hexahydrate

Synonym(s):

Foscarnet, Phosphonoformic acid trisodium salt hexahydrate

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About This Item

Linear Formula:
Na2O3PCO2Na · 6H2O
CAS Number:
34156-56-4
Molecular Weight:
300.04
MDL number:
MFCD00150176
UNSPSC Code:
12352100
PubChem Substance ID:
57654550
NACRES:
NA.22

form

powder

SMILES string

O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O

InChI

1S/CH3O5P.3Na.6H2O/c2-1(3)7(4,5)6;;;;;;;;;/h(H,2,3)(H2,4,5,6);;;;6*1H2/q;3*+1;;;;;;/p-3

InChI key

ILRVASBWNRYBFD-UHFFFAOYSA-K

Gene Information

human ... POLA1(5422) , POLD1(5424) , POLG(5428)
rat ... Slc17a1(171080)

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pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H341,H373

Hazard Classifications

Muta. 2 - STOT RE 2

target_organs

Kidney,Bone

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Triethylamine ≥99.5%

Sigma-Aldrich

471283

Triethylamine

Emily Rose et al.
Scientific reports, 9(1), 8798-8798 (2019-06-21)
How inorganic phosphate (Pi) homeostasis is regulated in Drosophila is currently unknown. We here identify MFS2 as a key Pi transporter in fly renal (Malpighian) tubules. Consistent with its role in Pi excretion, we found that dietary Pi induces MFS2
Tadashi Kato et al.
Calcified tissue international, 104(2), 201-206 (2018-10-21)
Nephronectin (Npnt), an extracellular matrix protein, is known to be a ligand of integrin α8β1, and it has also been known to play critical roles as various organs. In the present study, elevated extracellular inorganic phosphate (Pi) strongly inhibited the
Sampada Chande et al.
Scientific reports, 10(1), 3069-3069 (2020-02-23)
Low blood phosphate (Pi) reduces muscle function in hypophosphatemic disorders. Which Pi transporters are required and whether hormonal changes due to hypophosphatemia contribute to muscle function is unknown. To address these questions we generated a series of conditional knockout mice
Liudi Tang et al.
PLoS pathogens, 15(4), e1007742-e1007742 (2019-04-27)
Persistent hepatitis B virus (HBV) infection relies on the establishment and maintenance of covalently closed circular (ccc) DNA, a 3.2 kb episome that serves as a viral transcription template, in the nucleus of an infected hepatocyte. Although evidence suggests that
Jocelyne Piret et al.
Journal of virology, 89(8), 4636-4644 (2015-02-13)
DNA polymerases of the Herpesviridae and bacteriophage RB69 belong to the α-like DNA polymerase family. In spite of similarities in structure and function, the RB69 enzyme is relatively resistant to foscarnet, requiring the mutation V478W in helix N to promote

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