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D9775

Sigma-Aldrich

N,N-Dimethyldodecylamine N-oxide

≥99% (titration)

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

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About This Item

Linear Formula:
CH3(CH2)11N(O)(CH3)2
CAS Number:
1643-20-5
Molecular Weight:
229.40
Beilstein/REAXYS Number:
1769927
EC Number:
216-700-6
MDL number:
MFCD00002049
UNSPSC Code:
12161900
PubChem Substance ID:
329798912

description

non-ionic

assay

≥99% (titration)

mol wt

229.40 g/mol

technique(s)

NMR: suitable
enzyme immunoassay: suitable

mp

132-133 °C (lit.)

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC[N+](C)(C)[O-]

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

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General description

N,N-Dimethyldodecylamine N-oxide is a non-denaturing zwitterionic surfactant with a critical micelle concentration (CMC) of approximately 1 mM. It is used to solubilize proteins and to study the conformation and molecular interactions of macromolecules.

Other Notes

This product has been replaced by 40234-SIGMA | N,N-Dimethyldodecylamine N-oxide BioXtra, ≥99.0% (NT)

replaced by

Product No.
Description
Pricing

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SLBB3895V
BCBG7696V
040M1523V
BCBD4613V
BCBD8381V

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Gang Huang et al.
Nature communications, 10(1), 835-835 (2019-02-21)
A high throughput single-molecule method for identifying peptides and sequencing proteins based on nanopores could reduce costs and increase speeds of sequencing, allow the fabrication of portable home-diagnostic devices, and permit the characterization of low abundance proteins and heterogeneity in
Gang Huang et al.
Nature communications, 8(1), 935-935 (2017-10-19)
Biological nanopores are nanoscale sensors employed for high-throughput, low-cost, and long read-length DNA sequencing applications. The analysis and sequencing of proteins, however, is complicated by their folded structure and non-uniform charge. Here we show that an electro-osmotic flow through Fragaceatoxin
Vasyl Bondarenko et al.
Biochimica et biophysica acta, 1818(5), 1261-1268 (2012-03-01)
The α4β2 nicotinic acetylcholine receptor (nAChR) is the predominant heteromeric subtype of nAChRs in the brain, which has been implicated in numerous neurological conditions. The structural information specifically for the α4β2 and other neuronal nAChRs is presently limited. In this
Achim Stocker et al.
Journal of structural biology, 152(2), 140-145 (2005-10-18)
Recently, we reported the cloning of the atp operon encoding for the F(1)F(0)-ATP synthase from the extremely thermoalkaliphilic bacterium Bacillus sp. strain TA2.A1. In this study, the genes encoding the F(1) moiety of the enzyme complex were cloned from the
Xiaoyi Deng et al.
Journal of medicinal chemistry, 57(12), 5381-5394 (2014-05-08)
Malaria is one of the most serious global infectious diseases. The pyrimidine biosynthetic enzyme Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) is an important target for antimalarial chemotherapy. We describe a detailed analysis of protein-ligand interactions between DHODH and a triazolopyrimidine-based inhibitor
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