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Sigma-Aldrich

N,N-Dimethyldodecylamine N-oxide

BioXtra, ≥99.0% (NT)

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

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5 G
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About This Item

Linear Formula:
CH3(CH2)11N(O)(CH3)2
CAS Number:
1643-20-5
Molecular Weight:
229.40
Beilstein/REAXYS Number:
1769927
EC Number:
216-700-6
MDL number:
MFCD00002049
UNSPSC Code:
12161902
PubChem Substance ID:
57649946
NACRES:
NA.26

$733.00

Available to ship onApril 08, 2025Details

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description

non-ionic

Quality Level

200

product line

BioXtra

assay

≥99.0% (NT)

form

powder

mol wt

229.40 g/mol

technique(s)

protein quantification: suitable

impurities

≤0.03% peroxides (as H2O2)

CMC

1-2 mM

mp

132-133 °C (lit.)

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤100 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC[N+](C)(C)[O-]

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

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General description

N,N-Dimethyldodecylamine N-oxide is a non-denaturing zwitterionic surfactant with a critical micelle concentration (CMC) of approximately 1 mM. It is used to solubilize proteins and to study the conformation and molecular interactions of macromolecules.

Application

N,N-Dimethyldodecylamine N-oxide has been used in the cell lysis and resuspension of cell pellets for western blot analysis.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK7525
BCCM2621
0000331372
0000229351
0000222777

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J Karlovská et al.
Biophysical chemistry, 119(1), 69-77 (2005-10-15)
Sarcoplasmic reticulum Ca-transporting ATPase (EC 3.6.1.38) was isolated from rabbit white muscle, purified and reconstituted into vesicles of synthetic diacylphosphatidylcholines with monounsaturated acyl chains using the cholate dilution method. In fluid bilayers at 37 degrees C, the specific activity of
Stefanie Keis et al.
Journal of bacteriology, 188(11), 3796-3804 (2006-05-19)
The F(1)F(o)-ATP synthases of alkaliphilic bacteria exhibit latent ATPase activity, and for the thermoalkaliphile Bacillus sp. strain TA2.A1, this activity is intrinsic to the F(1) moiety. To study the mechanism of ATPase inhibition, we developed a heterologous expression system in
Rie Kakehashi et al.
Journal of colloid and interface science, 289(2), 498-503 (2005-08-23)
In the hydrogen ion titration of micelles, the degree of ionization of the micelle at a given pH has to be evaluated to obtain a pKa value of micelles (Ka being the proton dissociation constant) at the pH. We compared
Eugenio Daviso et al.
Journal of the American Chemical Society, 133(42), 16754-16757 (2011-10-04)
Several techniques rely on electron-nuclear interactions to boost the polarization of nuclear spins in the solid phase. Averaging out of anisotropic interactions as a result of molecular tumbling strongly reduces the applicability of such hyperpolarization approaches in liquids. Here we
Sebastian Hiller et al.
Science (New York, N.Y.), 321(5893), 1206-1210 (2008-08-30)
The voltage-dependent anion channel (VDAC) mediates trafficking of small molecules and ions across the eukaryotic outer mitochondrial membrane. VDAC also interacts with antiapoptotic proteins from the Bcl-2 family, and this interaction inhibits release of apoptogenic proteins from the mitochondrion. We
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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