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MAB8510

Sigma-Aldrich

Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7

clone 1B7, Chemicon®, from mouse

Synonym(s):

Metapneumovirus

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

clone

1B7, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable

isotype

IgG2a

shipped in

wet ice

Specificity

Recognizes Human Metapneumoviruses. Reacts against both A and B antigenic groups and subgroups 1 and 2.

Immunogen

Epitope: localized to the M1 protein human metapneumovirus
MPV CAN98-75

Application

Detect Human Metapneumovirus 75.1 using this Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7 validated for use in ELISA & IF.
ELISA
Immunofluorescence:
It is difficult to grow the metapneumovirus in standard cell lines. LLC-MK2 can be used for culture; acetone fixation is recommended. See Ebihara, 2005.

Optimal dilutions must be determined by the end user
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
Protein A purified

Storage and Stability

Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Metapneumovirus positive patient sample

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Detection of respiratory viruses by molecular methods.
Mahony, JB
Clinical Microbiology Reviews null
Akitaka Fujita et al.
Frontiers in immunology, 11, 432-432 (2020-03-29)
Viral infections of the airway can exacerbate respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD), and accelerate disease progression. Phosphoinositide 3-kinase (PI3K)δ, a class 1A PI3K, has been studied as a potential target for achieving anti-oncogenic and
Marlies Ballegeer et al.
mBio, 15(1), e0212223-e0212223 (2023-12-20)
Human metapneumovirus (hMPV) is an important respiratory pathogen for which no licensed antivirals or vaccines exist. Single-domain antibodies represent promising antiviral biologics that can be easily produced and formatted. We describe the isolation and detailed characterization of two hMPV-neutralizing single-domain
James B Mahony
Expert review of anti-infective therapy, 8(11), 1273-1292 (2010-11-16)
The appearance of eight new respiratory viruses in the human population in the past 9 years, including two new pandemics (SARS coronavirus in 2003 and swine-origin influenza A/H1N1 in 2009), has tested the ability of virology laboratories to develop diagnostic
Detection of human metapneumovirus in clinical samples by immunofluorescence staining of shell vial centrifugation cultures prepared from three different cell lines.
Landry, ML; Ferguson, D; Cohen, S; Peret, TC; Erdman, DD
Journal of Clinical Microbiology null

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