Skip to Content
MilliporeSigma
All Photos(3)

Key Documents

View All Documentation

C11804

Sigma-Aldrich

4-Sulfamoylbenzoic acid

97%

Synonym(s):

4-Carboxybenzenesulfonamide, Benzoic acid 4-sulfamide

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

Linear Formula:
HO2CC6H4SO2NH2
CAS Number:
138-41-0
Molecular Weight:
201.20
Beilstein/REAXYS Number:
1875393
EC Number:
205-327-4
MDL number:
MFCD00007938
UNSPSC Code:
12352108
PubChem Substance ID:
24892374
NACRES:
NA.22

Quality Level

200

assay

97%

form

powder

reaction suitability

reagent type: cross-linking reagent

mp

285-295 °C (lit.)

functional group

carboxylic acid
sulfonamide

SMILES string

O=S(C(C=C1)=CC=C1C(O)=O)(N)=O

InChI

1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)

InChI key

UCAGLBKTLXCODC-UHFFFAOYSA-N

Gene Information

human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238) , CA9(768)

Looking for similar products? Visit Product Comparison Guide

General description

4-Sulfamoylbenzoic acid also known as 4-carboxybenzenesulfonamide, is a sulfonamide derivative of benzoic acid. It is a crosslinking reagent used widely in organic synthesis.

Application

4-Sulfamoylbenzoic acid is used to synthesize 4-sulfamoylbenzoyl chloride and isocyanate derivatives. Additionally, it can be used in the esterification of alcohols.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Furan-based inhibitors of pyruvate dehydrogenase: SAR study, biochemical evaluation and computational analysis
AHY Chan
Organic & Biomolecular Chemistry, 21, 1755-1763 (2023)
Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies
MF Abo-Ashour
Bioorganic Chemistry, 87, 794-802 (2019)
Microwave assisted synthesis of novel hybrid tacrine-sulfonamide derivatives and investigation of their antioxidant and anticholinesterase activities
R Ulus
Bioorganic Chemistry, 245-255 (2017)
Jean-Yves Winum et al.
Journal of medicinal chemistry, 48(6), 2121-2125 (2005-03-18)
Targeting proteins overexpressed in hypoxic tumors is as an important means of controlling cancer disease. One such protein is the carbonic anhydrase (CA) isoenzyme IX, which in some types of tumors is overexpressed 150-200-fold. We report here a series of
Daniel J Orton et al.
Analytical chemistry, 90(1), 737-744 (2017-11-22)
To better understand disease conditions and environmental perturbations, multiomic studies combining proteomic, lipidomic, and metabolomic analyses are vastly increasing in popularity. In a multiomic study, a single sample is typically extracted in multiple ways, and various analyses are performed using
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service