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W381306

Sigma-Aldrich

Taurine

≥98%, FG

Synonym(s):

2-Aminoethanesulfonic acid

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About This Item

Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
FEMA Number:
3813
Beilstein/REAXYS Number:
1751215
EC Number:
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
16.056
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

FG
Halal
Kosher

agency

meets purity specifications of JECFA

reg. compliance

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117

assay

≥98%

mp

>300 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

SMILES string

NCCS(O)(=O)=O

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

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General description

Taurine is a sulfur-containing amino acid mainly found in animal tissues. In mammals, it is reported to play an important role in the normal development of fetuses and neonates. Taurine is also one of the key ingredients in energy drinks.

Application


  • Efficacy of taurine-enhanced enteral nutrition in improving the outcomes of critically ill patients: A systematic review and meta-analysis.: This meta-analysis evaluates the effectiveness of taurine-enhanced enteral nutrition in critically ill patients. The results indicate that taurine supplementation significantly improves patient outcomes, including reduced inflammation and enhanced recovery rates (Zhang et al., 2024).

  • Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.: This systematic review and meta-analysis demonstrate that taurine supplementation can significantly reduce the risk of metabolic syndrome. The findings support taurine′s potential as a therapeutic agent in managing metabolic health and preventing related diseases (Tzang et al., 2024).

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Safety issues associated with commercially available energy drinks.
Clauson KA, et al.
Journal of the American Pharmaceutical Association, 48(3), e55-e67 (2008)
Taurine supplementation to a low protein diet during foetal and early postnatal life restores a normal proliferation and apoptosis of rat pancreatic islets.
Boujendar S, et al.
Diabetologia, 45(6), 856-866 (2002)
Marlene Wewalka et al.
The Journal of clinical endocrinology and metabolism, 99(4), 1442-1451 (2014-01-18)
Bile acids (BAs) are newly recognized signaling molecules in glucose and energy homeostasis. Differences in BA profiles with type 2 diabetes mellitus (T2D) remain incompletely understood. The objective of the study was to assess serum BA composition in impaired glucose-tolerant
M Axelson et al.
Hepatology (Baltimore, Md.), 31(6), 1305-1312 (2000-05-29)
The biosynthesis of bile acids by primary cultures of normal human hepatocytes has been investigated. A general and sensitive method for the isolation and analysis of sterols and bile acids was used, based on anion exchange chromatography and gas chromatography-mass
Tsutomu Suzuki et al.
Wiley interdisciplinary reviews. RNA, 2(3), 376-386 (2011-10-01)
Mitochondrial DNA mutations that cause mitochondrial dysfunction are responsible for a wide spectrum of human diseases, referred to as mitochondrial diseases. Pathogenic point mutations are found frequently in genes encoding mitochondrial (mt) tRNAs, indicating that impaired functioning of mutant mt

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