V900452
Hypoxanthine
Vetec™, reagent grade, 98%
Synonym(s):
6-Hydroxypurine
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C5H4N4O
CAS Number:
Molecular Weight:
136.11
Beilstein/REAXYS Number:
5811
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
Pricing and availability is not currently available.
Recommended Products
grade
reagent grade
product line
Vetec™
assay
98%
form
powder
mp
>300 °C (lit.)
solubility
formic acid: water (2:1): 50 mg/mL, clear to slightly hazy
SMILES string
O=C1NC=Nc2nc[nH]c12
InChI
1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
Inchi Key
FDGQSTZJBFJUBT-UHFFFAOYSA-N
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Application
Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Xinyu Yu et al.
iScience, 26(1), 105725-105725 (2022-12-30)
The emergence and spread of artemisinin-tolerant malaria parasites threatens malaria control programmes worldwide. Mutations in the propeller domain of the Kelch13 protein confer Plasmodium falciparum artemisinin resistance (ART-R). ART-R is linked to the reduced susceptibility of temporary growth-arrested ring-stage parasites
Tomáš Tichý et al.
European journal of medicinal chemistry, 55, 307-314 (2012-08-04)
Hexadecyloxypropyl esters of acyclic nucleoside phosphonates containing guanine (G) or hypoxanthine (Hx) and a (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] [(S)-HPMP] or 2-(2-phosphonoethoxy)ethyl (PEE) acyclic moiety have been prepared. The activity of the prodrugs was evaluated in vitro against different virus families. Whereas ester derivatives of
Abdulazeez T Lawal et al.
Food chemistry, 135(4), 2982-2987 (2012-09-18)
A potentiometric enzyme electrode for detection of hypoxanthine (Hx) in fish meat is described. The sensor was developed by entrapment of xanthine oxidase (XOD) and ferrocene carboxylic acid (Fc) into polypyrrole (PPy) film during galvanostatic polymerisation film formation. The responses
Chien-Wei Hou et al.
The American journal of Chinese medicine, 40(5), 979-991 (2012-08-30)
Hyperuricemia causes gouty arthritis, kidney disease, heart disease, and other diseases. Xanthine oxidase (XOD) and urate transporters play important roles in urate homeostasis. Numerous plants have been identified as XOD inhibitors. Longan seeds are known to contain high levels of
Chia-Tung Wu et al.
Cardiovascular research, 102(3), 487-496 (2014-03-07)
Fibroblasts, which play an important role in cardiac function/dysfunction, including arrhythmogenesis, have voltage-dependent (Kv) currents of unknown importance. Here, we assessed the differential expression of Kv currents between atrial and ventricular fibroblasts from control dogs and dogs with an atrial
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