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25 MG
$527.00
$527.00
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25 MG
$527.00
About This Item
UNSPSC Code:
12352202
NACRES:
NA.77
$527.00
Usually ships in 2 weeks.
Notify Me
Get notified when this item is ready to ship via email.
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assay
>95% (HPLC)
form
lyophilized powder
mol wt
~445.4
shipped in
ambient
storage temp.
−20°C
Biochem/physiol Actions
A selective inhibitor of the p70 ribosomal S6 kinase (S6K). Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 uM with no activity at GSK3beta and Erk1/2 at 10 uM (2). Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K. Cell permeable.
Reconstitution
Formulated as a lyophilized powder. May be dissolved in DMSO (1 mg/mL) or DMF (3 mg/mL, warm).
Storage and Stability
Store desiccated as supplied at -20°C for up to 3 years. Store solutions at -20°C for up to 3 months.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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