SML2300
ADA-07
≥95% (HPLC)
Synonym(s):
5-(adamantan-1-yl)-3-(hydroxyimino) indolin-2-one
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C18H20N2O2
CAS Number:
Molecular Weight:
296.36
UNSPSC Code:
12352200
NACRES:
NA.77
Product SML2300 is not currently sold in your country. Contact Technical Service
Recommended Products
assay
≥95% (HPLC)
form
powder
color
yellow to brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(/C1=N\O)NC(C1=C2)=CC=C2C34C[C@@H](C5)C[C@@H](C[C@@H]5C4)C3
Biochem/physiol Actions
ADA-07 is a potent and selective T-LAK cell-originated protein kinase (TOPK) inhibitor that binds to ATP-binding pocket. ADA-07 suppresses SUV-induced phosphorylation of ERK1/2, p38, and JNKs and subsequently inhibited AP-1 activity, and reduces SUV-induced skin carcinogenesis.
potent and selective TOPK inhibitor that binds to ATP-binding pocket; reduces SUV-induced skin carcinogenesis
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Ge Gao et al.
Molecular cancer therapeutics, 16(9), 1843-1854 (2017-06-29)
Cumulative exposure to solar ultraviolet (SUV) irradiation is regarded as the major etiologic factor in the development of skin cancer. The activation of the MAPK cascades occurs rapidly and is vital in the regulation of SUV-induced cellular responses. The T-LAK
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
